BPTF is a scaffolding subunit of the nucleosome remodeling factor (NURF) complex. Here the authors show that BPTF is upregulated in prostate cancer cells, increases chromatin accessibility at Androgen Receptor (AR)-binding sites, and stabilizes the AR-FOXA1 complex.
- Hee-Young Jeon
- Sudeep Khadka
- Jianfei Qi