Yang et al. demonstrate that the rice lectin OsChtBL1 accumulates in the food canal of insect vectors, creating a barrier that hinders feeding and reduces rice stripe virus (RSV) transmission. RSV counters this by using its P2 protein to recruit the host E3 ubiquitin ligase OsRING18, leading to OsChtBL1 degradation.
- Zihang Yang
- Wei Wu
- Zongtao Sun