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Showing 1–6 of 6 results
Advanced filters: Author: Heike Bischoff-Ferrari Clear advanced filters

  • Applying epigenetic clocks to samples from the DO-HEALTH trial, Bischoff-Ferrari et al. report a small protective effect of omega-3 supplementation over 3 years on several clocks and an additive protective effect of omega-3, vitamin D and exercise using PhenoAge.

    • Heike A. Bischoff-Ferrari
    • Stephanie Gängler
    • Steve Horvath
    ResearchOpen Access
    Nature Aging
    Volume: 5, P: 376-385

  • The Integrated Care for Older People (ICOPE) program was developed to promote a function-centered and individualized approach to healthy aging, but it is not yet widely implemented. In this study, de Souto Barreto et al. used early-stage ICOPE data collected in primary healthcare from more than 20,000 older adults to characterize patterns of intrinsic capacity impairment and associated odds of frailty and disability.

    • Philipe de Souto Barreto
    • Emmanuel Gonzalez-Bautista
    • Bruno Vellas
    Research
    Nature Aging
    Volume: 4, P: 1279-1289

  • On 22 March 2023, the Geroscience Translational Research & International Conference on Frailty and Sarcopenia Research (ICFSR) Task Force met in Toulouse, France to discuss avenues to foster the development of intrinsic capacity and frailty clinical trials under a geroscience perspective. A synthesis of these discussions and a set of recommendations are presented in this Meeting Report.

    • Philipe de Souto Barreto
    • Yves Rolland
    • Nathan K. LeBrasseur
    News & Views
    Nature Aging
    Volume: 3, P: 1474-1479

  • In January 2024, a Hevolution Alliance for Aging Biomarkers thinktank convened at Cold Spring Harbor to discuss the framework for creating an open and diverse data resource for developing reliable aging biomarkers. As the funding for this initiative has now been confirmed, we summarize recommendations and key milestones for its implementation.

    • Toshiko Tanaka
    • Felipe Sierra
    • Yousin Suh
    News & Views
    Nature Aging
    Volume: 5, P: 188-192

  • Geroscience is becoming a major hope for preventing age-related diseases and loss of function by targeting biological mechanisms of aging. This article reports a discussion of a research Task Force on the challenges posed by the clinical research in Geroscience so that future gerotherapeutic clinical trials can be conducted successfully.

    • Yves Rolland
    • Felipe Sierra
    • Alex Zhavoronkov
    ReviewsOpen Access
    Nature Communications
    Volume: 14, P: 1-10