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Showing 1–3 of 3 results
Advanced filters: Author: Helena M. Tubb Clear advanced filters

  • Analyses of in vivo models, cell lines and patient-derived samples show that apolipoprotein B mRNA-editing catalytic subunit 3B (APOBEC3B) not only restrains lung tumor initiation but also that its upregulation is associated with resistance to targeted therapies. This study highlights the complex and context-dependent role of APOBEC3B in lung cancer.

    • Deborah R. Caswell
    • Philippe Gui
    • Charles Swanton
    ResearchOpen Access
    Nature Genetics
    Volume: 56, P: 60-73

  • Emerging SARS-CoV-2 variants of concern were detected early and multiple cases of virus spread not captured by clinical genomic surveillance were identified using high-resolution wastewater and clinical sequencing.

    • Smruthi Karthikeyan
    • Joshua I. Levy
    • Rob Knight
    ResearchOpen Access
    Nature
    Volume: 609, P: 101-108