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Showing 1–2 of 2 results
Advanced filters: Author: Helena Marrero Clear advanced filters

  • Enzyme engineering is opening up new chemistries. Here, the authors report enzymes engineered to contain two biological active sites — also showing that one site can be converted to a metal-complex catalyst — and demonstrate the utility of such dual sites in a range of catalytic processes.

    • Sandra Alonso
    • Gerard Santiago
    • Manuel Ferrer
    Research
    Nature Catalysis
    Volume: 3, P: 319-328

  • The incidence of NAFLD, which increases the risk of liver cancer, is increasing to epidemic proportions. This Review outlines the correlations between liver cancer and NAFLD-related cirrhosis, and the role of the metabolic syndrome in the development of liver cancer. Advances in understanding the progression of NAFLD to hepatocellular carcinoma from preclinical models will also be discussed.

    • Gregory A. Michelotti
    • Mariana V. Machado
    • Anna Mae Diehl
    Reviews
    Nature Reviews Gastroenterology & Hepatology
    Volume: 10, P: 656-665