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Showing 1–4 of 4 results

Advanced filters: Author: Helena Shomar Clear advanced filters

Viperin immunity evolved across the tree of life through serial innovations on a conserved scaffold

Systematic analysis of viperin sequences, a family of immune genes that are highly conserved across diverse prokaryotes and eukaryotes, shows that eukaryotic viperins were acquired from archaea and provides information about their evolutionary dynamics.

Helena Shomar
Héloïse Georjon
Aude Bernheim
Research04 Jul 2024
Nature Ecology & Evolution

Volume: 8, P: 1667-1679
Prokaryotic viperins produce diverse antiviral molecules

Eukaryotic viperins originated from a clade of bacterial and archaeal proteins that catalyse the production of antiviral molecules.

Aude Bernheim
Adi Millman
Rotem Sorek
Research16 Sept 2020
Nature

Volume: 589, P: 120-124
Metabolic engineering of a carbapenem antibiotic synthesis pathway in Escherichia coli

Efficient production of a simple carbapenem antibiotic in Escherichia coli is achieved by a combination of feedback-resistant enzymes for increased precursor biosynthesis and inhibition of fatty acid synthesis for tolerance toward the toxic product.

Helena Shomar
Sophie Gontier
Gregory Bokinsky
Research25 Jun 2018
Nature Chemical Biology

Volume: 14, P: 794-800
Genome sequence and characterization of Streptomyces phages Vanseggelen and Verabelle, representing two new species within the genus Camvirus

Véronique Ongenae
Annabel Kempff
Dennis Claessen
ResearchOpen Access17 Nov 2023
Scientific Reports

Volume: 13, P: 1-10