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Showing 1–7 of 7 results
Advanced filters: Author: Henrik Kehlet Clear advanced filters

  • Whether a midline or transverse incision is used in abdominal surgery depends mainly on the disease, anatomy and potential effects on wound healing, pain and postoperative complications. Decisions can, however, be based on a surgeon's experience and preference, as the procedures' respective benefits remain to be clearly delineated.

    • Henrik Kehlet
    News & Views
    Nature Reviews Gastroenterology & Hepatology
    Volume: 6, P: 571-572

  • Fast-track colonic surgery can be successfully implemented in community hospitals. Two recent studies provide further evidence of the benefits of this fast-track surgical approach on postoperative gastrointestinal recovery after laparoscopic and open procedures. The issue is no longer whether fast-track colonic surgery is better than standard care, but how to improve the approach and its implementation.

    • Henrik Kehlet
    News & Views
    Nature Reviews Gastroenterology & Hepatology
    Volume: 8, P: 539-540

  • Postoperative ileus is an undesirable stress response to major abdominal surgery that can cause abdominal pain, postoperative nausea and vomiting, distention, delayed passage of stool and the inability to take in sufficient fluids and solids. In this Review, the author considers the techniques currently available to prevent or reduce the duration of postoperative ileus, including the concept of multimodal postoperative rehabilitation (fast-track surgery).

    • Henrik Kehlet
    Reviews
    Nature Clinical Practice Gastroenterology & Hepatology
    Volume: 5, P: 552-558

  • Glucocorticoids (GC) are commonly used to suppress undesirable inflammatory responses. Here the authors show, using hi-dimensional flow cytometry data, that GC treatment following major surgeries alters adaptive immunity without significant modulation of innate immune responses or pain/functional impairment.

    • Edward A. Ganio
    • Natalie Stanley
    • Brice Gaudilliere
    ResearchOpen Access
    Nature Communications
    Volume: 11, P: 1-12