Advanced search

Filter By:

Journal Check one or more journals to show results from those journals only.

Choose more journals

Article type Check one or more article types to show results from those article types only.
Subject Check one or more subjects to show results from those subjects only.
Date Choose a date option to show results from those dates only.

Custom date range

Clear all filters
Sort by:
Showing 1–12 of 12 results
Advanced filters: Author: Henrike Maatz Clear advanced filters

  • Maatz, Lindberg et al. identify molecular alterations and immune response changes in endomyocardial biopsies from patients with myocarditis after COVID-19 infection, after anti-COVID-19 vaccination or from non-COVID-related causes.

    • Henrike Maatz
    • Eric L. Lindberg
    • Carsten Tschöpe
    ResearchOpen Access
    Nature Cardiovascular Research
    Volume: 4, P: 330-345

  • Single-cell and single-nucleus RNA sequencing are used to construct a cellular atlas of the human heart that will aid further research into cardiac physiology and disease.

    • Monika Litviňuková
    • Carlos Talavera-López
    • Sarah A. Teichmann
    ResearchOpen Access
    Nature
    Volume: 588, P: 466-472

  • Alternative splicing affects the function of many cardiac proteins, including that of the sarcomeric protein titin. Wei Guo et al. now show that the gene RBM20, previously identified as mutated in some individuals with dilated cardiomyopathy, is a splicing factor that regulates the alternative splicing of the gene encoding titin and many other key cardiac genes.

    • Wei Guo
    • Sebastian Schafer
    • Michael Gotthardt
    Research
    Nature Medicine
    Volume: 18, P: 766-773

  • An integrated analysis of over 100 single-cell and single-nucleus transcriptomics studies illustrates severe acute respiratory syndrome coronavirus 2 viral entry gene coexpression patterns across different human tissues, and shows association of age, smoking status and sex with viral entry gene expression in respiratory cell populations.

    • Christoph Muus
    • Malte D. Luecken
    • Xiaohui Zhang
    Research
    Nature Medicine
    Volume: 27, P: 546-559

  • Fibroblast-specific Il-11 expression causes heart and kidney fibrosis and organ failure, whereas IL-11 inhibition prevents fibroblast activation and organ fibrosis, indicating that IL-11 inhibition is a potential therapeutic strategy to treat fibrotic diseases.

    • Sebastian Schafer
    • Sivakumar Viswanathan
    • Stuart A. Cook
    Research
    Nature
    Volume: 552, P: 110-115

  • In this Review, Noseda and colleagues provide an overview of the technical challenges in the experimental design of single-cell and single-nucleus transcriptomics studies, and describe novel findings derived from transcriptomics studies for each major cardiac cell type in both health and disease, and from development to adulthood.

    • Antonio M. A. Miranda
    • Vaibhao Janbandhu
    • Michela Noseda
    Reviews
    Nature Reviews Cardiology
    Volume: 20, P: 289-308

  • In this Review, Tschöpe and colleagues summarize and evaluate the available evidence on the pathogenesis, diagnosis and treatment of myocarditis and inflammatory cardiomyopathy, with special focus on virus-induced and virus-associated myocarditis. The authors also identify knowledge gaps, appraise available experimental models and propose future directions for the field.

    • Carsten Tschöpe
    • Enrico Ammirati
    • Sophie Van Linthout
    Reviews
    Nature Reviews Cardiology
    Volume: 18, P: 169-193

  • The LifeTime initiative is an ambitious, multidisciplinary programme that aims to improve healthcare by tracking individual human cells during disease processes and responses to treatment in order to develop and implement cell-based interceptive medicine in Europe.

    • Nikolaus Rajewsky
    • Geneviève Almouzni
    • Frauke Zipp
    Reviews
    Nature
    Volume: 587, P: 377-386