3-hydroxy-γ-butyrolactone (3HBL) is a building block for many valuable drugs and is synthesized via a costly industrial process. Martin et al. engineer a novel biosynthetic pathway for the inexpensive production of 3HBL and other 3-hydroxyacids in E. coli.
- Collin H. Martin
- Himanshu Dhamankar
- Kristala L.J. Prather