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Showing 1–9 of 9 results
Advanced filters: Author: Holger Marschall Clear advanced filters

  • Sliding of drops over solid surface is a common phenomenon, but it remains impossible to predict the sliding velocity due to numerous dissipation channels causing drop friction. Li et al. show that dynamic wetting is determined by a dimensionless friction coefficient, which is a material parameter.

    • Xiaomei Li
    • Francisco Bodziony
    • Hans-Jürgen Butt
    ResearchOpen Access
    Nature Communications
    Volume: 14, P: 1-10

  • The sliding of a water drop on a surface is traditionally described by taking flow within the drop and contact-line friction into account. Now, evidence shows that electric forces can also substantially affect water-on-surface sliding dynamics.

    • Xiaomei Li
    • Pravash Bista
    • Hans-Jürgen Butt
    ResearchOpen Access
    Nature Physics
    Volume: 18, P: 713-719

  • The genetic basis of metabolic diseases is incompletely understood. Here, by high-throughput phenotyping of 2,016 knockout mouse strains, Rozman and colleagues identify candidate metabolic genes, many of which are associated with unexplored regulatory gene networks and metabolic traits in human GWAS.

    • Jan Rozman
    • Birgit Rathkolb
    • Martin Hrabe de Angelis
    ResearchOpen Access
    Nature Communications
    Volume: 9, P: 1-16

  • Systemic dissection of sexually dimorphic phenotypes in mice is lacking. Here, Karp and the International Mouse Phenotype Consortium show that approximately 10% of qualitative traits and 56% of quantitative traits in mice as measured in laboratory setting are sexually dimorphic.

    • Natasha A. Karp
    • Jeremy Mason
    • Jacqueline K. White
    ResearchOpen Access
    Nature Communications
    Volume: 8, P: 1-12

  • The full extent of the genetic basis for hearing impairment is unknown. Here, as part of the International Mouse Phenotyping Consortium, the authors perform a hearing loss screen in 3006 mouse knockout strains and identify 52 new candidate genes for genetic hearing loss.

    • Michael R. Bowl
    • Michelle M. Simon
    • Steve D. M. Brown
    ResearchOpen Access
    Nature Communications
    Volume: 8, P: 1-11

  • Discovery of causal variants for monogenic disorders has been facilitated by whole exome and genome sequencing, but does not provide a diagnosis for all patients. Here, the authors propose a Full Spectrum of Intolerance to Loss-of-Function (FUSIL) categorization that integrates gene essentiality information to aid disease gene discovery.

    • Pilar Cacheiro
    • Violeta Muñoz-Fuentes
    • Coleen Kane
    ResearchOpen Access
    Nature Communications
    Volume: 11, P: 1-16