Zhen Zhang, Chao Ran et al. show that whether or not polysaccharides injure the liver depends on their ability to keep endotoxin-bearing bacteria at bay and induce antimicrobial peptide (AMP) expression in zebrafish. They suggest polysaccharides can protect the liver only when AMPs are induced through HIF1α.
- Zhen Zhang
- Chao Ran
- Zhi-gang Zhou
