Nature Search

Publisher Correction: Neddylation inhibition induces glutamine uptake and metabolism by targeting CRL3^SPOP E3 ligase in cancer cells

Qiyin Zhou
Wenyu Lin
Yi Sun
Amendments and CorrectionsOpen Access14 Jun 2022
Nature Communications

Volume: 13, P: 1
Tumorigenic transformation by CPI-17 through inhibition of a merlin phosphatase

A phosphatase that activates the tumour suppressor protein merlin is identified. An endogenous inhibitor of this phosphatase is often upregulated in human tumours and may contribute to the development of cancer by inactivating merlin.

Hongchuan Jin
Tobias Sperka
Helen Morrison
Research03 Aug 2006
Nature

Volume: 442, P: 576-579
Neddylation inhibition induces glutamine uptake and metabolism by targeting CRL3^SPOP E3 ligase in cancer cells

Neddylation inhibition has been reported as a therapy for cancer. Here, the authors show that neddylation inhibition increases glutamine metabolism by stabilizing glutamine transporter ASCT2, therefore targeting ASCT2 improves the anti-cancer effect of neddylation inhibitors.

Qiyin Zhou
Wenyu Lin
Yi Sun
ResearchOpen Access31 May 2022
Nature Communications

Volume: 13, P: 1-18
SIRT1 deacetylated and stabilized XRCC1 to promote chemoresistance in lung cancer

Neelum Aziz Yousafzai
Qiyin Zhou
Xian Wang
ResearchOpen Access01 May 2019
Cell Death & Disease

Volume: 10, P: 1-12
Sirt1 deacetylates and stabilizes p62 to promote hepato-carcinogenesis

Lifeng Feng
Miaoqin Chen
Hongchuan Jin
ResearchOpen Access14 Apr 2021
Cell Death & Disease

Volume: 12, P: 1-13
Achieving adjustable elasticity with non-affine to affine transition

A non-affine to affine transition in elasticity occurs with the change of system topology in a packing-derived network, which enables the tuning of elastic moduli and Poisson’s ratio.

Xiangying Shen
Chenchao Fang
Lei Xu
Research01 Jul 2021
Nature Materials

Volume: 20, P: 1635-1642
COPS5 amplification and overexpression confers tamoxifen-resistance in ERα-positive breast cancer by degradation of NCoR

The corepressor NCoR is required for tamoxifen-mediated ERα-dependent transcriptional repression. Here, the authors show that COPS5 confers tamoxifen-resistance through the degradation of NCOR, the recruitment of the co-activator PCAF to ERα binding sites and the subsequent ERα transcriptional activity.

Renquan Lu
Xiaobo Hu
Lin Guo
ResearchOpen Access04 Jul 2016
Nature Communications

Volume: 7, P: 1-13
Impaired autophagic degradation of lncRNA ARHGAP5-AS1 promotes chemoresistance in gastric cancer

Liyuan Zhu
Yiran Zhu
Hongchuan Jin
ResearchOpen Access16 May 2019
Cell Death & Disease

Volume: 10, P: 1-16
BigNeuron: a resource to benchmark and predict performance of algorithms for automated tracing of neurons in light microscopy datasets

This resource describes a collection of neurons from a variety of light microscopy-based datasets, which can serve as a gold standard for testing automated tracing algorithms, as shown by comparison of the performance of 35 algorithms.

Linus Manubens-Gil
Zhi Zhou
Hanchuan Peng
Research17 Apr 2023
Nature Methods

Volume: 20, P: 824-835
Appraising the role of circulating concentrations of micro-nutrients in epithelial ovarian cancer risk: A Mendelian randomization analysis

Yan Guo
Yunlong Lu
Hongchuan Jin
ResearchOpen Access30 Apr 2020
Scientific Reports

Volume: 10, P: 1-9
The tumor suppressor Wnt inhibitory factor 1 is frequently methylated in nasopharyngeal and esophageal carcinomas

Stephen L Chan
Yan Cui
Qian Tao
Research26 Mar 2007
Laboratory Investigation

Volume: 87, P: 644-650
The NF2 tumor suppressor merlin interacts with Ras and RasGAP, which may modulate Ras signaling

Yan Cui
Susann Groth
Helen Morrison
ResearchOpen Access16 Jul 2019
Oncogene

Volume: 38, P: 6370-6381
EGFR TKIs impair lysosome-dependent degradation of SQSTM1 to compromise the effectiveness in lung cancer

Lixian Yang
Shilong Ying
Hongchuan Jin
ResearchOpen Access12 Jul 2019
Signal Transduction and Targeted Therapy

Volume: 4, P: 1-11
Long non-coding RNA NEAT1 confers oncogenic role in triple-negative breast cancer through modulating chemoresistance and cancer stemness

Vivian Yvonne Shin
Jiawei Chen
Ava Kwong
ResearchOpen Access20 Mar 2019
Cell Death & Disease

Volume: 10, P: 1-10
Competing Risk Analyses of Medullary Carcinoma of Breast in Comparison to Infiltrating Ductal Carcinoma

Dongjun Dai
Rongkai Shi
Xian Wang
ResearchOpen Access17 Jan 2020
Scientific Reports

Volume: 10, P: 1-11
CD69 enhances immunosuppressive function of regulatory T-cells and attenuates colitis by prompting IL-10 production

Lei Yu
Fei Yang
Hongchuan Jin
ResearchOpen Access05 Sept 2018
Cell Death & Disease

Volume: 9, P: 1-14
Neddylation inhibitor MLN4924 suppresses growth and migration of human gastric cancer cells

Huiyin Lan
Zaiming Tang
Yi Sun
ResearchOpen Access11 Apr 2016
Scientific Reports

Volume: 6, P: 1-12
RNA-based therapeutics: an overview and prospectus

Yiran Zhu
Liyuan Zhu
Hongchuan Jin
ReviewsOpen Access23 Jul 2022
Cell Death & Disease

Volume: 13, P: 1-15
Linking the YTH domain to cancer: the importance of YTH family proteins in epigenetics

Rongkai Shi
Shilong Ying
Hongchuan Jin
ReviewsOpen Access01 Apr 2021
Cell Death & Disease

Volume: 12, P: 1-14
The regulation of protein translation and its implications for cancer

Ping Song
Fan Yang
Xian Wang
ReviewsOpen Access18 Feb 2021
Signal Transduction and Targeted Therapy

Volume: 6, P: 1-9
Targeting nuclear acid-mediated immunity in cancer immune checkpoint inhibitor therapies

Miaoqin Chen
Shiman Hu
Lifeng Feng
ReviewsOpen Access20 Nov 2020
Signal Transduction and Targeted Therapy

Volume: 5, P: 1-14
Long non-coding RNAs involved in autophagy regulation

Lixian Yang
Hanying Wang
Hongchuan Jin
ReviewsOpen Access05 Oct 2017
Cell Death & Disease

Volume: 8, P: e3073
N6-methyladenosine links RNA metabolism to cancer progression

Dongjun Dai
Hanying Wang
Xian Wang
ReviewsOpen Access26 Jan 2018
Cell Death & Disease

Volume: 9, P: 1-13

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Publisher Correction: Neddylation inhibition induces glutamine uptake and metabolism by targeting CRL3^SPOP E3 ligase in cancer cells

Tumorigenic transformation by CPI-17 through inhibition of a merlin phosphatase

Neddylation inhibition induces glutamine uptake and metabolism by targeting CRL3^SPOP E3 ligase in cancer cells

SIRT1 deacetylated and stabilized XRCC1 to promote chemoresistance in lung cancer

Sirt1 deacetylates and stabilizes p62 to promote hepato-carcinogenesis

Achieving adjustable elasticity with non-affine to affine transition

COPS5 amplification and overexpression confers tamoxifen-resistance in ERα-positive breast cancer by degradation of NCoR

Impaired autophagic degradation of lncRNA ARHGAP5-AS1 promotes chemoresistance in gastric cancer

BigNeuron: a resource to benchmark and predict performance of algorithms for automated tracing of neurons in light microscopy datasets

Appraising the role of circulating concentrations of micro-nutrients in epithelial ovarian cancer risk: A Mendelian randomization analysis

The tumor suppressor Wnt inhibitory factor 1 is frequently methylated in nasopharyngeal and esophageal carcinomas

The NF2 tumor suppressor merlin interacts with Ras and RasGAP, which may modulate Ras signaling

EGFR TKIs impair lysosome-dependent degradation of SQSTM1 to compromise the effectiveness in lung cancer

Long non-coding RNA NEAT1 confers oncogenic role in triple-negative breast cancer through modulating chemoresistance and cancer stemness

Competing Risk Analyses of Medullary Carcinoma of Breast in Comparison to Infiltrating Ductal Carcinoma

CD69 enhances immunosuppressive function of regulatory T-cells and attenuates colitis by prompting IL-10 production

Neddylation inhibitor MLN4924 suppresses growth and migration of human gastric cancer cells

RNA-based therapeutics: an overview and prospectus

Linking the YTH domain to cancer: the importance of YTH family proteins in epigenetics

The regulation of protein translation and its implications for cancer

Targeting nuclear acid-mediated immunity in cancer immune checkpoint inhibitor therapies

Long non-coding RNAs involved in autophagy regulation

N6-methyladenosine links RNA metabolism to cancer progression

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