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Finerenone versus spironolactone in patients with chronic kidney disease and type 2 diabetes: a target trial emulation

The relative benefits of finerenone vs spironolactone in CKD with T2D are unclear. Here the authors show that in >2,200 matched patients, finerenone lowers risks of cardiovascular and kidney events, death, and hyperkalemia compared with spironolactone.

Chung-An Wang
Hsuan-Wen Lai
Vin-Cent Wu
ResearchOpen Access31 Oct 2025
Nature Communications

Volume: 16, P: 1-10
Nuclear targeting of the betanodavirus B1 protein via two arginine-rich domains induces G1/S cell cycle arrest mediated by upregulation of p53/p21

Yu-Chin Su
Latif Reshi
Jiann-Ruey Hong
ResearchOpen Access15 Feb 2018
Scientific Reports

Volume: 8, P: 1-12

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Finerenone versus spironolactone in patients with chronic kidney disease and type 2 diabetes: a target trial emulation

Nuclear targeting of the betanodavirus B1 protein via two arginine-rich domains induces G1/S cell cycle arrest mediated by upregulation of p53/p21

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