Advanced search

Filter By:

Journal Check one or more journals to show results from those journals only.

Choose more journals

Article type Check one or more article types to show results from those article types only.
Subject Check one or more subjects to show results from those subjects only.
Date Choose a date option to show results from those dates only.

Custom date range

Clear all filters
Sort by:
Showing 1–2 of 2 results
Advanced filters: Author: Hugh Trahair Clear advanced filters

  • Here they demonstrate a therapeutic intervention elevating levels of CYP450-derived lipids to control the expansion of intermediate monocytes in tissue and peripheral blood, presenting a first in class therapeutic approach for treating chronic inflammatory disease.

    • Olivia V. Bracken
    • Parinaaz Jalali
    • Derek W. Gilroy
    ResearchOpen Access
    Nature Communications
    Volume: 17, P: 1-17

  • The authors show that cutaneous immunity is attenuated during aging due to the recruitment, by senescent fibroblasts, of inflammatory monocytes, which in turn inhibit resident memory T cell activation. Inhibition of p38 MAPK signaling blocks the recruitment and function of these monocytes and restores immunity.

    • Emma S. Chambers
    • Milica Vukmanovic-Stejic
    • Arne N. Akbar
    Research
    Nature Aging
    Volume: 1, P: 101-113