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Advanced filters: Author: Hui-Da Ma Clear advanced filters

  • In this study, Hu et al. identify a new mechanism through which sirtuin-4 fine-tunes urea cycle flux through decarbamylation of ornithine transcarbamylase to ensure proper ammonia detoxification upon increased amino acid catabolism.

    • Song-Hua Hu
    • Yu-Yang Feng
    • Shi-Min Zhao
    Research
    Nature Metabolism
    Volume: 5, P: 626-641