A main function of fat cells is to store fuel for future use, which is released when the fat is broken down in a process called lipolysis. Here Hei Sook Sul and colleagues describe a new enzyme in fat, AdPLA, that inhibits lipolysis and shows that genetic deletion results in protection from obesity in two mouse models.
- Kathy Jaworski
- Maryam Ahmadian
- Hei Sook Sul
