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Showing 1–2 of 2 results
Advanced filters: Author: Hussein Shehade Clear advanced filters

  • Radiotherapy can enhance the antitumour immune response. Here, the authors show that resistance to radiation in breast cancer cells can be due to Axl expression that suppresses antigen presentation though MHCI, promotes NF-κB signalling, and enhances cytokine release promoting a suppressive myeloid microenvironment.

    • Todd A. Aguilera
    • Marjan Rafat
    • Amato J. Giaccia
    ResearchOpen Access
    Nature Communications
    Volume: 7, P: 1-14

  • Detavernier et al. show that localized waves of epigenetic programming regulate the differentiation process of Ly6Chi monocytes during oral infection by Toxoplasma gondii, which are dominated by STAT1 in the bone marrow and AP-1/NF-kB in the periphery. This study provides insight into how monocytes are differentiated in response to inflammatory cues.

    • Aurélie Detavernier
    • Abdulkader Azouz
    • Stanislas Goriely
    ResearchOpen Access
    Communications Biology
    Volume: 2, P: 1-14