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Showing 1–2 of 2 results
Advanced filters: Author: I. Iacovache Clear advanced filters

  • Near-atomistic models of the prepore and membrane-inserted pore conformations derived from a combination of crystallography, cryo-EM, single-particle analysis, molecular simulation and modeling reveal a swirling mechanism of membrane insertion and pore formation by aerolysin.

    • Matteo T Degiacomi
    • Ioan Iacovache
    • Matteo Dal Peraro
    Research
    Nature Chemical Biology
    Volume: 9, P: 623-629

  • The centriole is an organelle composed of rings of SAS-6 proteins that form a cartwheel structure. Here the authors develop a cell-free system to examine core cartwheel assembly ofC. reinhardtiiproteins and discover that CrSAS-6 has autonomous properties that facilitates self-organized stacking of pairs of rings.

    • P. Guichard
    • V. Hamel
    • P. Gönczy
    ResearchOpen Access
    Nature Communications
    Volume: 8, P: 1-9