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IAIN DAVIDSON
WILLIAM NOBLE
Research30 Jan 1992
Nature

Volume: 355, P: 403-404
CTCF is a DNA-tension-dependent barrier to cohesin-mediated loop extrusion

CTCF is sufficient to block loop extruding cohesin in a DNA tension dependent manner, and induces loop extrusion direction switching and loop shrinkage.

Iain F. Davidson
Roman Barth
Jan-Michael Peters
ResearchOpen Access19 Apr 2023
Nature

Volume: 616, P: 822-827
Accelerated waning of the humoral response to COVID-19 vaccines in obesity

Epidemiological analyses coupled with immunological phenotyping suggest that humoral immunity induced by COVID-19 vaccines wanes more rapidly in individuals with severe obesity compared to individuals with a BMI within the normal range.

Agatha A. van der Klaauw
Emily C. Horner
James E. D. Thaventhiran
ResearchOpen Access11 May 2023
Nature Medicine

Volume: 29, P: 1146-1154
Probing met represser–operator recognition in solution

Yi-Yuan He
Teresa McNally
Peter G. Stockley
Research01 Oct 1992
Nature

Volume: 359, P: 431-433
PD-L1⁺ plasma cells suppress T lymphocyte responses in patients with sepsis and mouse sepsis models

Sepsis induces a period of immunosuppression which can be problematic in the face of subsequent infectious challenge. Here the authors show the presence of PD-L1 expressing regulatory plasma cells that can inhibit T cells in a murine model and in patients with sepsis.

Morgane Gossez
Clara Vigneron
Fabienne Venet
ResearchOpen Access28 Mar 2025
Nature Communications

Volume: 16, P: 1-17
Identification of 12 new susceptibility loci for different histotypes of epithelial ovarian cancer

Paul Pharoah and colleagues report the results of a large genome-wide association study of ovarian cancer. They identify new susceptibility loci for different epithelial ovarian cancer histotypes and use integrated analyses of genes and regulatory features at each locus to predict candidate susceptibility genes, including OBFC1.

Catherine M Phelan
Karoline B Kuchenbaecker
Paul D P Pharoah
Research27 Mar 2017
Nature Genetics

Volume: 49, P: 680-691
MCM complexes are barriers that restrict cohesin-mediated loop extrusion

Single-nucleus Hi-C of embryos, polymer simulations and single-molecule imaging collectively reveal that MCM complexes influence genome folding and gene expression by impeding DNA loop extrusion.

Bart J. H. Dequeker
Matthias J. Scherr
Kikuë Tachibana
ResearchOpen Access18 May 2022
Nature

Volume: 606, P: 197-203
Wolffish Antifreeze Protein from Transgenic Drosophila

Derrick E. Rancourt
Iain D. Peters
Peter L. Davies
Research01 May 1990
Bio/Technology

Volume: 8, P: 453-457
Mechanisms leading to an acute rise in intraocular pressure in retinal vein occlusion

Alec M Ansons
Louis Clearkin
Iain Bryce
Research01 May 1990
Eye

Volume: 4, P: 439-444
Vortex phase matching as a strategy for schooling in robots and in fish

Whether and how fish might benefit from swimming in schools is an ongoing intriguing debate. Li et al. conduct experiments with biomimetic robots and also with real fish to reveal a new behavioural strategy by which followers can exploit the vortices shed by a near neighbour.

Liang Li
Máté Nagy
Iain D. Couzin
ResearchOpen Access26 Oct 2020
Nature Communications

Volume: 11, P: 1-9
Wapl is an essential regulator of chromatin structure and chromosome segregation

Depletion of the cohesin-associated protein Wapl in mice is shown to increase the residence time of cohesin on DNA, which leads to clustering of cohesin in axial structures, and causes chromatin condensation in interphase chromosomes; the findings suggest that cohesin could have an architectural role in interphase chromosome organization.

Antonio Tedeschi
Gordana Wutz
Jan-Michael Peters
Research25 Aug 2013
Nature

Volume: 501, P: 564-568
Testing pseudotopological and nontopological models for SMC-driven DNA loop extrusion against roadblock-traversal experiments

Roman Barth
Biswajit Pradhan
Cees Dekker
ResearchOpen Access19 May 2023
Scientific Reports

Volume: 13, P: 1-11
Gain-of-function mutations in IFIH1 cause a spectrum of human disease phenotypes associated with upregulated type I interferon signaling

Yanick Crow, Sun Hur and colleagues show that gain-of-function mutations in IFIH1 cause a spectrum of neural and immunological phenotypes associated with enhanced interferon signaling. The mutations increase the affinity of IFIH1 for RNA, leading to immune upregulation and inflammatory disease.

Gillian I Rice
Yoandris del Toro Duany
Yanick J Crow
Research30 Mar 2014
Nature Genetics

Volume: 46, P: 503-509
Host methylation predicts SARS-CoV-2 infection and clinical outcome

Konigsberg et al. profile DNA methylation in blood samples from SARS-CoV-2 cases and controls. The authors use machine learning to classify infected vs. non-infected individuals and predict clinical outcomes related to disease severity.

Iain R. Konigsberg
Bret Barnes
Kathleen C. Barnes
ResearchOpen Access26 Oct 2021
Communications Medicine

Volume: 1, P: 1-10
Forest-linked livelihoods in a globalized world

The landscape of forest and human activity is ever shifting, but new large-scale trends are causing exceptional changes and potential space for new conservation and development for communities dependent on forests.

Johan A. Oldekop
Laura Vang Rasmussen
Sarah J. Wilson
Reviews30 Nov 2020
Nature Plants

Volume: 6, P: 1400-1407
Genome folding through loop extrusion by SMC complexes

Chromatin loops are proposed to be formed through loop extrusion by structural maintenance of chromosomes (SMC) complexes. Recent studies have shown that the SMC complexes condensin and cohesin are indeed able to extrude DNA, and caused a paradigm shift in our understanding of genome organization and the cellular functions of SMC complexes.

Iain F. Davidson
Jan-Michael Peters
Reviews25 Mar 2021
Nature Reviews Molecular Cell Biology

Volume: 22, P: 445-464
Author Correction: Testing pseudotopological and nontopological models for SMC-driven DNA loop extrusion against roadblock-traversal experiments

Roman Barth
Biswajit Pradhan
Cees Dekker
Amendments and CorrectionsOpen Access18 Jul 2023
Scientific Reports

Volume: 13, P: 1-3
Schistocephalus parasite infection alters sticklebacks’ movement ability and thereby shapes social interactions

Jolle W. Jolles
Geoffrey P. F. Mazué
Iain D. Couzin
ResearchOpen Access23 Jul 2020
Scientific Reports

Volume: 10, P: 1-11
Dynamic single-cell phenotyping of immune cells using the microfluidic platform DropMap

This protocol describes a microfluidic platform for dynamic high-throughput analysis of the phenotypes of single cells. Cell-surface markers and secreted proteins are quantified and characterized by fluorescence detection using tailored immunoassays.

Yacine Bounab
Klaus Eyer
Christophe Védrine
Protocols12 Aug 2020
Nature Protocols

Volume: 15, P: 2920-2955
Ancient dog diets on the Pacific Northwest Coast: zooarchaeological and stable isotope modelling evidence from Tseshaht territory and beyond

Dylan Hillis
Iain McKechnie
Chris T. Darimont
ResearchOpen Access01 Oct 2020
Scientific Reports

Volume: 10, P: 1-12
AusTraits, a curated plant trait database for the Australian flora

Daniel Falster
Rachael Gallagher
Kasia Ziemińska
ResearchOpen Access30 Sept 2021
Scientific Data

Volume: 8, P: 1-20

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Language gap

CTCF is a DNA-tension-dependent barrier to cohesin-mediated loop extrusion

Accelerated waning of the humoral response to COVID-19 vaccines in obesity

Probing met represser–operator recognition in solution

PD-L1⁺ plasma cells suppress T lymphocyte responses in patients with sepsis and mouse sepsis models

Identification of 12 new susceptibility loci for different histotypes of epithelial ovarian cancer

MCM complexes are barriers that restrict cohesin-mediated loop extrusion

Wolffish Antifreeze Protein from Transgenic Drosophila

Mechanisms leading to an acute rise in intraocular pressure in retinal vein occlusion

Vortex phase matching as a strategy for schooling in robots and in fish

Wapl is an essential regulator of chromatin structure and chromosome segregation

Testing pseudotopological and nontopological models for SMC-driven DNA loop extrusion against roadblock-traversal experiments

Gain-of-function mutations in IFIH1 cause a spectrum of human disease phenotypes associated with upregulated type I interferon signaling

Host methylation predicts SARS-CoV-2 infection and clinical outcome

Forest-linked livelihoods in a globalized world

Genome folding through loop extrusion by SMC complexes

Author Correction: Testing pseudotopological and nontopological models for SMC-driven DNA loop extrusion against roadblock-traversal experiments

Schistocephalus parasite infection alters sticklebacks’ movement ability and thereby shapes social interactions

Dynamic single-cell phenotyping of immune cells using the microfluidic platform DropMap

Ancient dog diets on the Pacific Northwest Coast: zooarchaeological and stable isotope modelling evidence from Tseshaht territory and beyond

AusTraits, a curated plant trait database for the Australian flora

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