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Angiopoietin-like 3-derivative LNA043 for cartilage regeneration in osteoarthritis: a randomized phase 1 trial

The mechanism of action of LNA043—a novel disease-modifying osteoarthritis treatment candidate—is characterized in preclinical studies and through transcriptomic profiling of cartilage from patients with osteoarthritis in a phase 1 trial.

Nicole Gerwin
Celeste Scotti
Michaela Kneissel
ResearchOpen Access01 Dec 2022
Nature Medicine

Volume: 28, P: 2633-2645

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Angiopoietin-like 3-derivative LNA043 for cartilage regeneration in osteoarthritis: a randomized phase 1 trial

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