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Advanced filters: Author: Ikuko Miyaguchi Clear advanced filters

Transport and inhibition mechanism of the human SGLT2–MAP17 glucose transporter

Here, cryo-electron microscopy structures of sodium–glucose cotransporter 2, which is responsible for sugar reabsorption in the kidney and is a target for the treatment of type 2 diabetes, reveal a potential mechanism for cellular sugar uptake.

Masahiro Hiraizumi
Tomoya Akashi
Ikuko Miyaguchi
ResearchOpen Access06 Dec 2023
Nature Structural & Molecular Biology

Volume: 31, P: 159-169
Machine learning to estimate the local quality of protein crystal structures

Ikuko Miyaguchi
Miwa Sato
Mitsunori Ikeguchi
ResearchOpen Access08 Dec 2021
Scientific Reports

Volume: 11, P: 1-13

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Transport and inhibition mechanism of the human SGLT2–MAP17 glucose transporter

Machine learning to estimate the local quality of protein crystal structures

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