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Showing 1–5 of 5 results

Advanced filters: Author: Ikuyo Ichi Clear advanced filters

TTC39B deficiency stabilizes LXR reducing both atherosclerosis and steatohepatitis

In mice, deficiency in the high-density lipoprotein gene T39 stabilizes liver X receptor (LXR), reducing both atherosclerosis and steatohepatitis, suggesting that T39 inhibition could be an effective strategy for reducing these diseases.

Joanne Hsieh
Masahiro Koseki
Alan R. Tall
Research06 Jul 2016
Nature

Volume: 535, P: 303-307
The prevalence and clinical features of MYO7A-related hearing loss including DFNA11, DFNB2 and USH1B

Kizuki Watanabe
Shin-ya Nishio
Shunsuke Kondo
ResearchOpen Access09 Apr 2024
Scientific Reports

Volume: 14, P: 1-19
Cryo-EM analysis reveals human SID-1 transmembrane family member 1 dynamics underlying lipid hydrolytic activity

Structural and biochemical analysis of double-stranded RNA transporter SIDT1 reveals the conformational change associated with cholesterol binding and the causal relationship between pH, RNA binding, and ceramidase activity.

Yoshinori Hirano
Umeharu Ohto
Toshiyuki Shimizu
ResearchOpen Access29 May 2024
Communications Biology

Volume: 7, P: 1-10
Dietary 7-ketocholesterol exacerbates myocardial ischemia–reperfusion injury in mice through monocyte/macrophage-mediated inflammation

Tomoki Uchikawa
Tetsuya Matoba
Hiroyuki Tsutsui
ResearchOpen Access01 Sept 2022
Scientific Reports

Volume: 12, P: 1-15
Comprehensive analysis of syndromic hearing loss patients in Japan

Michie Ideura
Shin-ya Nishio
Shin-ichi Usami
ResearchOpen Access19 Aug 2019
Scientific Reports

Volume: 9, P: 1-13