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Showing 1–2 of 2 results
Advanced filters: Author: Ilan Gobius Clear advanced filters

  • Neuronal activity is known to increase myelination by oligodendrocytes in the mouse brain. Here, Mitew et al. demonstrate that chemogenetic manipulations of somatosensory axon activity both increase the generation of new oligodendrocytes and preferentially enhance myelination of the activated axons.

    • Stanislaw Mitew
    • Ilan Gobius
    • Ben Emery
    ResearchOpen Access
    Nature Communications
    Volume: 9, P: 1-16

  • Linda Richards, Paul Lockhart, Christel Depienne and colleagues identify heterozygous DCC mutations in four families and five sporadic individuals with agenesis of the corpus callosum (ACC). They report that DCC mutations result in variable dominant phenotypes with incomplete penetrance, including mirror movements and ACC associated with a favorable developmental prognosis.

    • Ashley P L Marsh
    • Delphine Heron
    • Christel Depienne
    Research
    Nature Genetics
    Volume: 49, P: 511-514