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Engineered E. coli Nissle 1917 for the delivery of matrix-tethered therapeutic domains to the gut

Anti-inflammatory treatments for gastrointestinal diseases can often have detrimental side effects. Here the authors engineer E. coli Nissle 1917 to create a fibrous matrix that has a protective effect in DSS-induced colitis mice.

Pichet Praveschotinunt
Anna M. Duraj-Thatte
Neel S. Joshi
ResearchOpen Access06 Dec 2019
Nature Communications

Volume: 10, P: 1-14

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