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Showing 1–7 of 7 results

Advanced filters: Author: Ilse Maes Clear advanced filters

A coronavirus assembly inhibitor that targets the viral membrane protein

High-throughput screening and hit optimization have led to the development of a small molecule, CIM-834, that targets the SARS-CoV-2 membrane protein and blocks assembly of the virus.

Manon Laporte
Dirk Jochmans
Johan Neyts
ResearchOpen Access26 Mar 2025
Nature

Volume: 640, P: 514-523
Diversity and dissemination of viruses in pathogenic protozoa

Heeren et al study the evolutionary genomics of leishmaniasis in Peru and Bolivia to show that parasite hybridization increases the prevalence, diversity and spread of viruses that have been previously associated with disease severity and treatment failure.

Senne Heeren
Ilse Maes
Frederik Van den Broeck
ResearchOpen Access15 Dec 2023
Nature Communications

Volume: 14, P: 1-15
Evolutionary genomics of Leishmania braziliensis across the neotropical realm

The first genome and continent-wide study of Leishmania braziliensis across South America reveals eco-epidemiologically distinct genetic groups in the Amazon and Atlantic Forests, offering new insights into the pathogen’s evolutionary history.

Senne Heeren
Mandy Sanders
Frederik Van den Broeck
ResearchOpen Access28 Nov 2024
Communications Biology

Volume: 7, P: 1-14
Persistent T cell unresponsiveness associated with chronic visceral leishmaniasis in HIV-coinfected patients

A longitudinal study of the circulatory cellular immunity of individuals co-infected with recurrent visceral leishmaniasis and HIV suggests that T cell unresponsiveness underlies visceral leishmaniasis chronicity.

Nicky de Vrij
Julia Pollmann
Wim Adriaensen
ResearchOpen Access03 May 2024
Communications Biology

Volume: 7, P: 1-13
Tracking of quiescence in Leishmania by quantifying the expression of GFP in the ribosomal DNA locus

Marlene Jara
Ilse Maes
Jorge Arevalo
ResearchOpen Access12 Dec 2019
Scientific Reports

Volume: 9, P: 1-12
Evaluation of whole genome amplification and bioinformatic methods for the characterization of Leishmania genomes at a single cell level

Hideo Imamura
Pieter Monsieurs
Malgorzata A. Domagalska
ResearchOpen Access14 Sept 2020
Scientific Reports

Volume: 10, P: 1-13
Personal, social and environmental predictors of daily fruit and vegetable intake in 11-year-old children in nine European countries

I De Bourdeaudhuij
S te Velde
K-I Klepp
Research16 May 2007
European Journal of Clinical Nutrition

Volume: 62, P: 834-841