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Showing 1–4 of 4 results
Advanced filters: Author: Iltefat Hamzavi Clear advanced filters

  • Vitiligo is a chronic, autoimmune, depigmenting disorder that has both physiological and psychological effects on affected individuals. In this Primer, Seneschal and colleagues provide an overview of the epidemiology, pathogenesis, diagnosis and management of the condition as well as of its effect on quality of life, and highlight current and emerging treatments.

    • Julien Seneschal
    • Jung Min Bae
    • Mauro Picardo
    Reviews
    Nature Reviews Disease Primers
    Volume: 11, P: 1-23

  • Richard Spritz and colleagues present a genome-wide association study of autoimmune vitiligo in 4,680 cases and 39,586 controls and report 23 new risk loci. Their results highlight specific pathways, including immune response, apoptosis and melanocyte function, that may be important in the pathobiology of autoimmune vitiligo.

    • Ying Jin
    • Genevieve Andersen
    • Richard A Spritz
    Research
    Nature Genetics
    Volume: 48, P: 1418-1424

  • Vitiligo is the most common depigmenting disorder globally. Here, the authors explore the interplay of metabolic disturbances, autoimmunity and cellular degeneration that lead to the dysfunction and destruction of melanocytes. Understanding these processes supports the development of more effective therapies.

    • Mauro Picardo
    • Maria L. Dell'Anna
    • Alain Taieb
    Reviews
    Nature Reviews Disease Primers
    Volume: 1, P: 1-16