Nature Search

Correction: Corrigendum: Sex-specific transcriptional signatures in human depression

Benoit Labonté
Olivia Engmann
Eric J Nestler
Amendments and Corrections01 Apr 2018
Nature Medicine

Volume: 24, P: 525
Cell- and layer-specific transcriptomic strategy for characterizing the molecular phenotype of rat cortical neurons using laser capture microdissection and massively parallel RNA sequencing

Michael L. Miller
Benjamin Chadwick
Yasmin L. Hurd
Research21 Mar 2019
Molecular Psychiatry

Volume: 24, P: 473
Early life stress alters transcriptomic patterning across reward circuitry in male and female mice

Early life stress alters behavioural response to adult stress in female mice. Here authors transcriptionally profile three brain regions involved in reward (ventral tegmental area, nucleus accumbens, and prefrontal cortex) in both male and female adult mice after early life and/or adult stress

Catherine Jensen Peña
Milo Smith
Eric J. Nestler
ResearchOpen Access08 Nov 2019
Nature Communications

Volume: 10, P: 1-13
Epigenetic regulation of brain region-specific microglia clearance activity

Microglia clearance activity in adult brain is regulated epigenetically and region-specifically to match neuronal attrition rates. Uncoupling this activity from neural apoptosis leads to aberrant microglia activation & neurodegenerative-like changes.

Pinar Ayata
Ana Badimon
Anne Schaefer
Research23 Jul 2018
Nature Neuroscience

Volume: 21, P: 1049-1060
Transcriptional and physiological adaptations in nucleus accumbens somatostatin interneurons that regulate behavioral responses to cocaine

While making up a small percentage of neurons in the nucleus accumbens, somatostatin interneurons may have important function in dopamine- and addiction-related behavior. Here, Ribeiro and colleagues show that somatostatin interneurons regulate behavioral responses to cocaine with physiological and transcriptomic changes.

Efrain A. Ribeiro
Marine Salery
Eric J. Nestler
ResearchOpen Access08 Aug 2018
Nature Communications

Volume: 9, P: 1-10
Estrogen receptor α drives pro-resilient transcription in mouse models of depression

Stress resilience is accompanied by broad changes in gene expression. This study shows that estrogen receptor α (ERα) is a key upstream regulator of these changes in the nucleus accumbens, and that overexpression of ERα increases behavioral resilience via a sex-specific transcriptional mechanism.

Zachary S. Lorsch
Yong-Hwee Eddie Loh
Eric J. Nestler
ResearchOpen Access16 Mar 2018
Nature Communications

Volume: 9, P: 1-11
Sex-specific transcriptional signatures in human depression

Brain-region-specific RNA-seq from humans with major depressive disorder reveals unique transcriptomic profiles in males and females, with little overlap.

Benoit Labonté
Olivia Engmann
Eric J Nestler
Research21 Aug 2017
Nature Medicine

Volume: 23, P: 1102-1111
Genome-wide transcriptional profiling of central amygdala and orbitofrontal cortex during incubation of methamphetamine craving

Hannah M. Cates
Xuan Li
Eric J. Nestler
Research20 Jul 2018
Neuropsychopharmacology

Volume: 43, P: 2426-2434
A novel role for E2F3b in regulating cocaine action in the prefrontal cortex

Hannah M. Cates
Rosemary C. Bagot
Eric J. Nestler
Research14 Dec 2018
Neuropsychopharmacology

Volume: 44, P: 776-784
Adolescent exposure to Δ⁹-tetrahydrocannabinol alters the transcriptional trajectory and dendritic architecture of prefrontal pyramidal neurons

Michael L. Miller
Benjamin Chadwick
Yasmin L. Hurd
ResearchOpen Access03 Oct 2018
Molecular Psychiatry

Volume: 24, P: 588-600
Tet1 in Nucleus Accumbens Opposes Depression- and Anxiety-Like Behaviors

Jian Feng
Catherine J Pena
Eric J Nestler
Research11 Jan 2017
Neuropsychopharmacology

Volume: 42, P: 1657-1669

Search

Correction: Corrigendum: Sex-specific transcriptional signatures in human depression

Cell- and layer-specific transcriptomic strategy for characterizing the molecular phenotype of rat cortical neurons using laser capture microdissection and massively parallel RNA sequencing

Early life stress alters transcriptomic patterning across reward circuitry in male and female mice

Epigenetic regulation of brain region-specific microglia clearance activity

Transcriptional and physiological adaptations in nucleus accumbens somatostatin interneurons that regulate behavioral responses to cocaine

Estrogen receptor α drives pro-resilient transcription in mouse models of depression

Sex-specific transcriptional signatures in human depression

Genome-wide transcriptional profiling of central amygdala and orbitofrontal cortex during incubation of methamphetamine craving

A novel role for E2F3b in regulating cocaine action in the prefrontal cortex

Adolescent exposure to Δ⁹-tetrahydrocannabinol alters the transcriptional trajectory and dendritic architecture of prefrontal pyramidal neurons

Tet1 in Nucleus Accumbens Opposes Depression- and Anxiety-Like Behaviors

Search

Quick links

Search

Filter By:

Search

Quick links