de Riedmatten et al. propose apparent diffusion coefficient functional MRI as a novel contrast for assessing functional connectivity in both grey matter and white matter, addressing the limitations of blood oxygen level-dependent fMRI in capturing white matter activity. Their study demonstrates that this novel methods provides a more reliable white matter connectivity measure, with higher inter-subject similarity and reduced sensitivity to vascular noise, making it a promising alternative for investigating whole-brain functional connectivity.
- Inès de Riedmatten
- Arthur P. C. Spencer
- Ileana O. Jelescu
