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Signal Transduction and Targeted Therapy (2)
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Showing 1–7 of 7 results

Advanced filters: Author: Ines Liebscher Clear advanced filters

Structural basis for the tethered peptide activation of adhesion GPCRs

Adhesion GPCRs involved in cell and matrix interactions signal through a distinct self-cleavage, self-activation mechanism.

Yu-Qi Ping
Peng Xiao
Jin-Peng Sun
Research13 Apr 2022
Nature

Volume: 604, P: 763-770
The mechanosensitive adhesion G protein-coupled receptor 133 (GPR133/ADGRD1) enhances bone formation

Juliane Lehmann
Hui Lin
Ines Liebscher
ResearchOpen Access30 Jun 2025
Signal Transduction and Targeted Therapy

Volume: 10, P: 1-17
The repertoire of Adhesion G protein-coupled receptors in adipocytes and their functional relevance

Tomáš Suchý
Christian Zieschang
Doreen Thor
ResearchOpen Access19 Mar 2020
International Journal of Obesity

Volume: 44, P: 2124-2136
The adhesion GPCR GPR116/ADGRF5 has a dual function in pancreatic islets regulating somatostatin release and islet development

In vitro, ex vivo, and in vivo analysis shows that the Adhesion GPCR ADGRF5/GPR116 regulates islet functionality. Activation of the receptor leads to an increase in somatostatin secretion whereas loss of the receptor results in metabolic changes.

Juliane Röthe
Robert Kraft
Doreen Thor
ResearchOpen Access16 Jan 2024
Communications Biology

Volume: 7, P: 1-14
Elevated expression of the adhesion GPCR ADGRL4/ELTD1 promotes endothelial sprouting angiogenesis without activating canonical GPCR signalling

David M. Favara
Ines Liebscher
Adrian L. Harris
ResearchOpen Access23 Apr 2021
Scientific Reports

Volume: 11, P: 1-13
Genetic basis of functional variability in adhesion G protein-coupled receptors

Alexander Bernd Knierim
Juliane Röthe
Torsten Schöneberg
ResearchOpen Access30 Jul 2019
Scientific Reports

Volume: 9, P: 1-15
Stachel-mediated activation of adhesion G protein-coupled receptors: insights from cryo-EM studies

Ines Liebscher
Torsten Schöneberg
Doreen Thor
Research HighlightsOpen Access09 Jul 2022
Signal Transduction and Targeted Therapy

Volume: 7, P: 1-2