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Showing 1–6 of 6 results
Advanced filters: Author: Insook Kim Clear advanced filters

  • Sensors based on localized surface plasmon resonance suffer from low figures of merit. Here, the authors achieve high refractive index sensitivities and figures of merit by introducing a chiral shape and the idea of engineering the material dispersion function.

    • Hyeon-Ho Jeong
    • Andrew G. Mark
    • Peer Fischer
    ResearchOpen Access
    Nature Communications
    Volume: 7, P: 1-7

  • When exposed to chronic endoplasmic reticulum (ER) stress, cells downregulate protein synthesis by inhibiting mTOR signalling. Park et al.identify Sestrin2 as a transcriptional target of the ER stress pathway and an important mediator of this protective response in the liver.

    • Hwan-Woo Park
    • Haeli Park
    • Jun Hee Lee
    Research
    Nature Communications
    Volume: 5, P: 1-11

  • While non-canonical, Atg5/Atg7-independent autophagy has been reported to occur, molecular details of alternative autophagy pathways remain unknown. Here, the authors report that the protein TRIM31 mediates alternative autophagy in intestinal cells, which protects against pathogenic bacteria.

    • Eun A. Ra
    • Taeyun A. Lee
    • Boyoun Park
    ResearchOpen Access
    Nature Communications
    Volume: 7, P: 1-15

  • Cellular defects in autophagy contribute to the development of fatty liver in obesity. Here, Park et al.reveal that hepatic autophagy is impaired by chronically elevated cytosolic calcium levels, and show that a clinically approved calcium channel blocker can improve metabolic parameters of obese mice.

    • Hwan-Woo Park
    • Haeli Park
    • Jun Hee Lee
    Research
    Nature Communications
    Volume: 5, P: 1-12