The fungus Candida albicans is ubiquitous and usually harmless in the human gut, but can also cause systemic infection. Here, Kakade et al. show that fungal secretion of an immunomodulatory toxin, candidalysin, activates a host IL-17-DUOX2 axis that regulates C. albicans colonization of the intestine.
- Pallavi Kakade
- Juan F. Burgueno
- Richard J. Bennett
