Sirtuins are involved in the regulation of responses to diverse types of cellular stress. Here the authors describe the SirT6-dependent cysteine monoubiquitination of the histone methyltransferase Suv39h1 as part of a regulatory circuit for the NF-κB pathway.
- Irene Santos-Barriopedro
- Laia Bosch-Presegué
- Alejandro Vaquero
