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Showing 1–7 of 7 results

Advanced filters: Author: Irina Leonardi Clear advanced filters

Characterising acute and chronic care needs: insights from the Global Burden of Disease Study 2019

Chronic care manages long-term, progressive conditions, while acute care handles short-term ones. Here, authors show chronic conditions account for most of the global health burden, with 68% of DALYs and 93% of YLDs attributed to chronic care needs.

Cecilia Anza-Ramirez
J. Jaime Miranda
Yves Miel H. Zuniga
ResearchOpen Access07 May 2025
Nature Communications

Volume: 16, P: 1-36
Author Correction: Immune regulation by fungal strain diversity in inflammatory bowel disease

Xin V. Li
Irina Leonardi
Iliyan D. Iliev
Amendments and Corrections20 Jul 2022
Nature

Volume: 608, P: E21
Statistical inference with a manifold-constrained RNA velocity model uncovers cell cycle speed modulations

VeloCycle is a manifold-constrained generative framework to estimate RNA velocity during the cell cycle.

Alex R. Lederer
Maxine Leonardi
Gioele La Manno
ResearchOpen Access31 Oct 2024
Nature Methods

Volume: 21, P: 2271-2286
Mycobiota-induced IgA antibodies regulate fungal commensalism in the gut and are dysregulated in Crohn’s disease

Mycobiota-induced IgA antibodies regulate fungal commensalism and are affected in Crohn’s disease.

Itai Doron
Marissa Mesko
Iliyan D. Iliev
Research22 Nov 2021
Nature Microbiology

Volume: 6, P: 1493-1504
Immune regulation by fungal strain diversity in inflammatory bowel disease

Genetically diverse Candida albicans strains in patients with inflammatory bowel disease secrete a toxin and aggravate IL-1β-dependent intestinal inflammation.

Xin V. Li
Irina Leonardi
Iliyan D. Iliev
Research16 Mar 2022
Nature

Volume: 603, P: 672-678
Preventive Trichuris suis ova (TSO) treatment protects immunocompetent rabbits from DSS colitis but may be detrimental under conditions of immunosuppression

Irina Leonardi
Alexandra Gerstgrasser
Isabelle Frey-Wagner
ResearchOpen Access28 Nov 2017
Scientific Reports

Volume: 7, P: 1-15
Fungal dysbiosis: immunity and interactions at mucosal barriers

Changes in the composition of the microbiota — also known as dysbiosis — are important contributors to inflammatory diseases. In this Review, the authors explore how disruptions in fungal communities can influence host immunity, and how the immune system has evolved to distinguish between fungal infection and dysbiosis.

Iliyan D. Iliev
Irina Leonardi
Reviews12 Jun 2017
Nature Reviews Immunology

Volume: 17, P: 635-646