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Showing 1–4 of 4 results
Advanced filters: Author: Iris Mildenberger Clear advanced filters

  • In this compassionate use study, treatment of adult patients with H3K27M-mutant diffuse midline glioma with a long peptide vaccine targeting H3K27M led to vaccine-induced peripheral T cell immune responses and encouraging clinical efficacy in the majority of patients, including a durable complete response.

    • Niklas Grassl
    • Isabel Poschke
    • Katharina Sahm
    ResearchOpen Access
    Nature Medicine
    Volume: 29, P: 2586-2592

  • Literature produced inconsistent findings regarding the links between extreme weather events and climate policy support across regions, populations and events. This global study offers a holistic assessment of these relationships and highlights the role of subjective attribution.

    • Viktoria Cologna
    • Simona Meiler
    • Amber Zenklusen
    ResearchOpen Access
    Nature Climate Change
    Volume: 15, P: 725-735

  • Sahm et al. evaluate clinical, imaging, and molecular data from a small cohort of patients with concurrent multiple sclerosis (MS) and gliomas. They report differential methylation of some immune-related loci in tumors from patients with MS, and that inflammatory disease activity can increase in these patients after brain tumor radiotherapy.

    • Katharina Sahm
    • Tobias Kessler
    • Michael Platten
    ResearchOpen Access
    Communications Medicine
    Volume: 3, P: 1-9