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Showing 1–7 of 7 results
Advanced filters: Author: Jürgen Appel Clear advanced filters

  • In a meta-analysis of 48 randomized trials of chronic kidney disease progression, reduction in the 6-month urinary albumin:creatinine ratio was associated with lower hazard ratios of established kidney disease endpoints, supporting the use of albuminuria change as a surrogate endpoint in clinical trials for chronic kidney disease.

    • Hiddo J. L. Heerspink
    • Willem H. Collier
    • Lesley A. Inker
    Research
    Nature Medicine
    Volume: 32, P: 281-287

  • Analyses of 475 ancient horse genomes show modern horses emerged around 2200 bce, coinciding with sudden expansion across Eurasia, refuting the narrative of large horse herds accompanying earlier migrations of steppe peoples across Europe.

    • Pablo Librado
    • Gaetan Tressières
    • Ludovic Orlando
    ResearchOpen Access
    Nature
    Volume: 631, P: 819-825

  • Magnetoelectric coupling allows switching of magnetic states via gate voltage pulses. Here the authors propose and demonstrate a purely antiferromagnetic magnetoelectric random access memory based on Cr2O3, reporting 50-fold reduction of writing threshold compared to ferromagnetic counterparts.

    • Tobias Kosub
    • Martin Kopte
    • Denys Makarov
    ResearchOpen Access
    Nature Communications
    Volume: 8, P: 1-7

  • Einstein–Podolsky–Rosen entanglement between a millimetre-size mechanical membrane oscillator and a collective atomic spin oscillator formed by an ensemble of caesium atoms is achieved, although the two systems are spatially separated by one metre.

    • Rodrigo A. Thomas
    • Michał Parniak
    • Eugene S. Polzik
    Research
    Nature Physics
    Volume: 17, P: 228-233

  • A meta-analysis of individual-level patient data from 66 clinical studies supports the utility of glomerular filtration rate as a surrogate endpoint in clinical trials for chronic kidney disease, with potential to enable detection of events earlier in the disease course.

    • Lesley A. Inker
    • Willem Collier
    • Mauro Saddelli
    Research
    Nature Medicine
    Volume: 29, P: 1867-1876

  • Ali Gharavi and colleagues report a genome-wide association analysis of IgA nephropathy in over 20,000 individuals of European and East Asian ancestry. They identify genome-wide significant signals at three new loci near VAV3, CARD9 and ITGAM-ITGAX and correlations between genetic risk and pathogen diversity.

    • Krzysztof Kiryluk
    • Yifu Li
    • Ali G Gharavi
    Research
    Nature Genetics
    Volume: 46, P: 1187-1196