Nature Search

Measurement of the Distance of Pulsar CP 0328

G. DE JAGER
A. G. LYNE
J. E. B. PONSONBY
Research12 Oct 1968
Nature

Volume: 220, P: 128-129
Evidence that Polywater is a Colloidal Silicate Sol

WILLARD D. BASCOM
EDWARD J. BROOKS
BRADFORD N. WORTHINGTON III
Research26 Dec 1970
Nature

Volume: 228, P: 1290-1293
The hydrolase LpqI primes mycobacterial peptidoglycan recycling

Bacterial growth and division require remodelling of the cell wall, which generates free peptidoglycan fragments. Here, Moynihan et al. show that Mycobacterium tuberculosis can recycle components of their peptidoglycan, and characterise a crucial enzyme required for this process.

Patrick J. Moynihan
Ian T. Cadby
Gurdyal S. Besra
ResearchOpen Access14 Jun 2019
Nature Communications

Volume: 10, P: 1-11
Do graded units of accretionary spheroids in the Barberton Greenstone Belt indicate Archaean deep water environment?

Ian G. Stanistreet
Maarten J. de Wit
Rodney E. P. Fripp
Research24 Sept 1981
Nature

Volume: 293, P: 280-284
Relationship between Maturity and Isoenzymes of Erythrocytic Carbonic Anhydrase in Newborn Infants

J B Moynihan
Research01 Aug 1977
Pediatric Research

Volume: 11, P: 871-873
Infra-Red Absorption Spectra and Protein-Sugar Interactions

J. D. S. GOULDEN
Research14 Jan 1956
Nature

Volume: 177, P: 85-86
η-Tocopherol (7-Methyltocol) : a New Tocopherol in Rice

J. GREEN
S. MARCINKIEWICZ
Research14 Jan 1956
Nature

Volume: 177, P: 86-87
The mycobacterial glycoside hydrolase LamH enables capsular arabinomannan release and stimulates growth

Here, Franklin et al show that the mycobacterial glycoside hydrolase LamH cleaves lipomannan and lipoarabinomannan from their lipid carrier, facilitating the export of the polysaccharide domain and signalling bacterial growth phase transition.

Aaron Franklin
Vivian C. Salgueiro
Patrick J. Moynihan
ResearchOpen Access09 Jul 2024
Nature Communications

Volume: 15, P: 1-15
Identification of d-arabinan-degrading enzymes in mycobacteria

Bacterial cell growth and division require the coordinated action of enzymes that synthesize and degrade cell wall polymers. Here, the authors identify enzymes that cleave the D-arabinan core of arabinogalactan, an unusual component of the cell wall of Mycobacterium tuberculosis and other mycobacteria.

Omar Al-Jourani
Samuel T. Benedict
Patrick J. Moynihan
ResearchOpen Access19 Apr 2023
Nature Communications

Volume: 14, P: 1-14
Do men with prostate or colorectal cancer seek different information and support from women with cancer?

M Boudioni
K McPherson
J Mossman
ResearchOpen Access28 Aug 2001
British Journal of Cancer

Volume: 85, P: 641-648
Intratumourally injected alum-tethered cytokines elicit potent and safer local and systemic anticancer immunity

The intratumoural injection of recombinantly expressed cytokines bound tightly to the common vaccine adjuvant aluminium hydroxide leads to weeks-long retention of the cytokines in the tumours with minimal side effects, as shown in multiple syngeneic mouse models.

Yash Agarwal
Lauren E. Milling
K. Dane Wittrup
Research10 Jan 2022
Nature Biomedical Engineering

Volume: 6, P: 129-143
Children’s state anxiety before MRI scanning and resting state functional connectivity in large scale brain networks

Purnima Qamar
Dana E. Díaz
Kalina J. Michalska
ResearchOpen Access16 Jan 2026
Scientific Reports

Volume: 16, P: 1-11
The Duodenal Spread of Pyloric Carcinoma

J H Fodden
Research01 Sept 1948
British Journal of Cancer

Volume: 2, P: 239-249
ALK peptide vaccination restores the immunogenicity of ALK-rearranged non-small cell lung cancer

Mota et al. show that poor response to immune checkpoint blockade in mouse models of ALK-rearranged NSCLC can be overcome by vaccination with an immunogenic ALK peptide and identify immunogenic human ALK peptides for future translational study.

Ines Mota
Enrico Patrucco
Roberto Chiarle
Research10 Jul 2023
Nature Cancer

Volume: 4, P: 1016-1035
Neoantigen-specific cytotoxic Tr1 CD4 T cells suppress cancer immunotherapy

Type 1 regulatory T cells (Tr1) represent a major obstacle that compromises naturally occurring and therapeutically induced tumour-specific immunity.

Hussein Sultan
Yoshiko Takeuchi
Robert D. Schreiber
ResearchOpen Access24 Jul 2024
Nature

Volume: 632, P: 182-191
Long-term effects on sexual function and fertility after treatment of testicular cancer

J T Hartmann
C Albrecht
C Bokemeyer
ResearchOpen Access23 Apr 1999
British Journal of Cancer

Volume: 80, P: 801-807
A PSA SNP associates with cellular function and clinical outcome in men with prostate cancer

The PSA (KLK3) genetic variant rs17632542 is associated with reduced prostate cancer risk and lower serum PSA levels, although the underlying reasons are unclear. Here, the authors show that this PSA variant reduced proteolytic activity and leads to smaller tumours, but also increases invasion and bone metastasis, indicating its dual risk association depending on tumour context; the variant is associated with both lower risk and poor clinical outcomes.

Srilakshmi Srinivasan
Thomas Kryza
Jyotsna Batra
ResearchOpen Access06 Nov 2024
Nature Communications

Volume: 15, P: 1-21
High-throughput quantitation of inorganic nanoparticle biodistribution at the single-cell level using mass cytometry

Assessing nanomaterials at the single cell level has proven to be complicated due to the limitations of existing techniques. Here, the authors utilised single-cell mass cytometry by time-of-flight as a label-free technique to analyse nanoparticle distribution within cells.

Yu-Sang Sabrina Yang
Prabhani U. Atukorale
Darrell J. Irvine
ResearchOpen Access17 Jan 2017
Nature Communications

Volume: 8, P: 1-11
Eradication of large established tumors in mice by combination immunotherapy that engages innate and adaptive immune responses

An immunotherapy consisting of a tumor-antigen targeting antibody, PD-1 blocking antibody, extended half-life recombinant IL-2 and a lymph-node-targeted T cell vaccine mobilized innate and adaptive immunity and eradicated large established tumors in a variety of mouse models.

Kelly D Moynihan
Cary F Opel
Darrell J Irvine
Research24 Oct 2016
Nature Medicine

Volume: 22, P: 1402-1410
Structural basis for activation of a diguanylate cyclase required for bacterial predation in Bdellovibrio

The initiation of prey invasion by the predatory bacterium Bdellovibrio bacteriovorus is governed by the activity of the diguanlylate cyclase DgcB. Here the authors show that the stimulus regulating DgcB activity is a phosphopeptide derived from DgcB itself and present the crystal structures of full-length DgcB and of its empty and peptide-bound sensor domain.

Richard W. Meek
Ian T. Cadby
Andrew L. Lovering
ResearchOpen Access09 Sept 2019
Nature Communications

Volume: 10, P: 1-13
A new family of bacterial ribosome hibernation factors

A study identifies a new bacterial ribosome hibernation factor, Balon, and describes its association with EF-Tu and its initiation of mRNA-independent hibernation during protein synthesis.

Karla Helena-Bueno
Mariia Yu. Rybak
Sergey V. Melnikov
ResearchOpen Access14 Feb 2024
Nature

Volume: 626, P: 1125-1132
Exploration by lamp light

Melissa J. Moore
News & Views27 Apr 1995
Nature

Volume: 374, P: 766-767
Pharmacokinetic tuning of protein–antigen fusions enhances the immunogenicity of T-cell vaccines

Tuning the pharmacokinetics of peptide-based antitumour vaccines by fusing the peptide epitopes to protein carriers optimizes the immunogenicity of the vaccines in mice.

Naveen K. Mehta
Roma V. Pradhan
Darrell J. Irvine
Research01 Jun 2020
Nature Biomedical Engineering

Volume: 4, P: 636-648
A lysozyme with altered substrate specificity facilitates prey cell exit by the periplasmic predator Bdellovibrio bacteriovorus

The bacterial periplasmic predator Bdellovibrio bacteriovorus deacetylates the peptidoglycan of the prey bacterium early upon invasion. Here, the authors identify and characterize a Bdellovibrio lysozyme that acts specifically on deacetylated peptidoglycan and is important for periplasmic exit.

Christopher J. Harding
Simona G. Huwiler
Andrew L. Lovering
ResearchOpen Access23 Sept 2020
Nature Communications

Volume: 11, P: 1-12
Disruption of the clock components CLOCK and BMAL1 leads to hypoinsulinaemia and diabetes

Circadian rhythms control many physiological functions. During periods of feeding, pancreatic islets secrete insulin to maintain glucose homeostasis — a rhythmic process that is disturbed in people with diabetes. These authors show that pancreatic islets contain their own clock: they have self-sustained circadian oscillations of CLOCK and BMAL1 genes and proteins, which are vital for the regulation of circadian rhythms. Without this clock, a cascade of cellular failure and pathology initiates the onset of diabetes mellitus.

Biliana Marcheva
Kathryn Moynihan Ramsey
Joseph Bass
Research18 Jun 2010
Nature

Volume: 466, P: 627-631
Targeting dendritic cells to accelerate T-cell activation overcomes a bottleneck in tuberculosis vaccine efficacy

A delay in T cell responses is postulated as a possible explanation for the limited efficacy of vaccines against tuberculosis. Here the authors demonstrate this T-cell block and remove it by activating endogenous dendritic cells or delivering activated dendritic cells to the lungs, enhancing immunity of mice toMycobacterium tuberculosis.

Kristin L. Griffiths
Mushtaq Ahmed
Shabaana A. Khader
ResearchOpen Access22 Dec 2016
Nature Communications

Volume: 7, P: 1-13
Liquid exfoliation of solvent-stabilized few-layer black phosphorus for applications beyond electronics

While phosphorene is an exciting new 2D material, techniques to produce it in large quantities in a stable, processable form are lacking. Here, the authors achieve this using liquid phase exfoliation and demonstrate the resultant nanosheets to be useful in a number of applications.

Damien Hanlon
Claudia Backes
Jonathan N. Coleman
ResearchOpen Access15 Oct 2015
Nature Communications

Volume: 6, P: 1-11
Loss-of-function mutations in the cathepsin C gene result in periodontal disease and palmoplantar keratosis

Carmel Toomes
Jacqueline James
Nalin S. Thakker
Research01 Dec 1999
Nature Genetics

Volume: 23, P: 421-424
Experimental evidence of high pressure decoupling between charge transport and structural dynamics in a protic ionic glass-former

Z. Wojnarowska
M. Rams-Baron
M. Paluch
ResearchOpen Access01 Aug 2017
Scientific Reports

Volume: 7, P: 1-8
Chromosomal markers in three species of the genus Mytilus (Mollusca: Bivalvia)

A Martínez-Lage
A González-Tizón
J Méndez
Research01 Apr 1995
Heredity

Volume: 74, P: 369-375
Identification of KasA as the cellular target of an anti-tubercular scaffold

Screens for bactericidal compounds have resulted in promising anti-tubercular hits. Here, the authors analyse in detail the target of an indazole sulfonamide (GSK3011724A), and find that it has a different mode of inhibition compared to other Kas inhibitors of fatty acid biosynthesis in bacteria.

Katherine A. Abrahams
Chun-wa Chung
Robert H. Bates
ResearchOpen Access01 Sept 2016
Nature Communications

Volume: 7, P: 1-13
Characterization of different chromatin types in Mytilus galloprovincialis L. after C-banding, fluorochrome and restriction endonuclease treatments

A Martínez-Lage
A González-Tizón
J Méndez
Research01 Mar 1994
Heredity

Volume: 72, P: 242-249
Positional cloning of zebrafish ferroportin1 identifies a conserved vertebrate iron exporter

Adriana Donovan
Alison Brownlie
Leonard I. Zon
Research17 Feb 2000
Nature

Volume: 403, P: 776-781
THPP target assignment reveals EchA6 as an essential fatty acid shuttle in mycobacteria

Tetrahydropyrazo[1,5-a]pyrimidine-3-carboxamide (THPP) targets the essential non-catalytic enoyl-CoA hydratase homologue EchA6 of Mycobacterium tuberculosis, and not MmpL3 as previously thought.

Jonathan A. G. Cox
Katherine A. Abrahams
Gurdyal S. Besra
Research18 Jan 2016
Nature Microbiology

Volume: 1, P: 1-10
A descriptive study of UK cancer genetics services: an emerging clinical response to the new genetics

D Wonderling
P Hopwood
K McPherson
ResearchOpen Access17 Jul 2001
British Journal of Cancer

Volume: 85, P: 166-170
Small business response to regulation: incorporating a behavioral perspective

Stuart Shapiro
Debra Borie-Holtz
ResearchOpen Access05 Aug 2020
Humanities and Social Sciences Communications

Volume: 7, P: 1-9
PatB1 is an O-acetyltransferase that decorates secondary cell wall polysaccharides

A chemically synthesized analog of Bacillus cereus secondary cell wall polysaccharide (SCWP) facilitates the identification of PatB1 as a SCWP O-acetyltransferase, and the structure of PatB1 provides insights into its catalytic mechanism.

David Sychantha
Dustin J Little
Anthony J Clarke
Research30 Oct 2017
Nature Chemical Biology

Volume: 14, P: 79-85
Squamous Cell Carcinoma Occurring in Asbestosis of the Lung

R J R Cureton
Research01 Sept 1948
British Journal of Cancer

Volume: 2, P: 249-253
Eddy-driven diazotroph distribution in the subtropical North Atlantic: horizontal variability prevails over particle sinking speed

Mesoscal eddies influence the distribution of marine diazotrophs in the North Atlantic, highlighting the potential role of particle-associated non-cyanobacterial diazotrophs (NCDs) on their contribution to nitrogen and carbon cycles.

E. Cerdán-García
X. A. Álvarez-Salgado
M. Benavides
ResearchOpen Access02 Aug 2024
Communications Biology

Volume: 7, P: 1-12
Science and Broadcasting

E. J. HOLMYARD
News01 Nov 1930
Nature

Volume: 126, P: 673-675
Dutch Pendulum Observations in the Atlantic and the Pacific

J. J. A. MULLER
News25 Dec 1926
Nature

Volume: 118, P: 930-932
A statistical study of sarcoma complicating Paget's disease of bone in three countries

C J Brackenridge
Research01 Aug 1979
British Journal of Cancer

Volume: 40, P: 194-200
Ultrastable glasses portray similar behaviour to ordinary glasses at high pressure

C. Rodríguez-Tinoco
M. González-Silveira
J. Rodríguez-Viejo
ResearchOpen Access03 Oct 2016
Scientific Reports

Volume: 6, P: 1-10
Development of Intermediate-Grade (Mantle Cell) and Low-Grade (Small Lymphocytic and Marginal Zone) Human Non-Hodgkin’s Lymphomas Xenotransplanted in Severe Combined Immunodeficiency Mouse Models

Jerry Bryant
Lan Pham
Richard J Ford
Research01 Apr 2000
Laboratory Investigation

Volume: 80, P: 557-573
Structure-based programming of lymph-node targeting in molecular vaccines

An amphiphile vaccine consisting of a peptide antigen or adjuvant cargo linked to a lipophilic tail is shown to have improved potency and safety in mice by targeting the lymph nodes.

Haipeng Liu
Kelly D. Moynihan
Darrell J. Irvine
Research16 Feb 2014
Nature

Volume: 507, P: 519-522
Perioperative factors associated with postoperative morbidity after emergency laparotomy: a retrospective analysis in a university teaching hospital

M. Ahmed
E. Garry
D. J. Buggy
ResearchOpen Access12 Oct 2020
Scientific Reports

Volume: 10, P: 1-9
Information needs of patients with cancer: results from a large study in UK cancer centres

V Jenkins
L Fallowfield
J Saul
ResearchOpen Access03 Jan 2001
British Journal of Cancer

Volume: 84, P: 48-51
Pathology, imaging, and treatment of cardiac tumours

Cardiac tumours include a wide array of both neoplastic and non-neoplastic entities. Cardiac tumours are often found incidentally during imaging by ultrasonography, CT, or MRI. In this Review, Maleszewiski and colleagues discuss the clinical presentation, imaging characteristics, pathological characteristics, and treatment of these lesions.

Joseph J. Maleszewski
Nandan S. Anavekar
Kyle W. Klarich
Reviews24 Apr 2017
Nature Reviews Cardiology

Volume: 14, P: 536-549
Feasibility study of a randomised controlled trial to compare (deferred) androgen deprivation therapy and cryotherapy in men with localised radiation-recurrent prostate cancer

M Salji
R Jones
H Y Leung
ResearchOpen Access19 Jun 2014
British Journal of Cancer

Volume: 111, P: 424-429
Sociodemographic and nutritional determinants of obesity in Belgium

MC Stam-Moraga
J Kolanowski
MD Kornitzer
Research12 Mar 1999
International Journal of Obesity

Volume: 23, P: S1-S9

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