Evf2 is a polyadenylated, noncoding RNA that is transcribed from the intergenic region of Dlx5 and Dlx6, which are genes for homeodomain transcriptional factors. The authors now show that the loss of Evf2 in mice results in a substantial reduction of GABAergic interneurons via interference with Dlx5/6 expression.
- Allison M Bond
- Michael J W VanGompel
- Jhumku D Kohtz