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British Journal of Cancer (35)
Leukemia (10)
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Advanced filters: Author: J Lankelma Clear advanced filters

Changes in subcellular doxorubicin distribution and cellular accumulation alone can largely account for doxorubicin resistance in SW-1573 lung cancer and MCF-7 breast cancer multidrug resistant tumour cells

GJ Schuurhuis
THM van Heijningen
J Lankelma
Research01 Nov 1993
British Journal of Cancer

Volume: 68, P: 898-908
Cortisol is transported by the multidrug resistance gene product P-glycoprotein

CK van Kalken
HJ Broxterman
G Giaccone
Research01 Feb 1993
British Journal of Cancer

Volume: 67, P: 284-289
Theoretical and practical considerations for the measurement of P-glycoprotein function in acute myeloid leukemia

HJ Broxterman
J Lankelma
GJ Schuurhuis
Research01 Jul 1997
Leukemia

Volume: 11, P: 1110-1118
Functional detection of MDR1/P170 and MRP/P190-mediated multidrug resistance in tumour cells by flow cytometry

N Feller
CM Kuiper
HJ Broxterman
Research01 Sept 1995
British Journal of Cancer

Volume: 72, P: 543-549
Highly sensitive and specific detection of P-glycoprotein function for haematological and solid tumour cells using a novel nucleic acid stain

HJ Broxterman
GJ Schuurhuis
HM Pinedo
Research01 Oct 1997
British Journal of Cancer

Volume: 76, P: 1029-1034
Genistein modulates the decreased drug accumulation in non-P-glycoprotein mediated multidrug resistant tumour cells

CHM Versantvoort
GJ Schuurhuis
HJ Broxterman
Research01 Nov 1993
British Journal of Cancer

Volume: 68, P: 939-946
Early multidrug resistance, defined by changes in intracellular doxorubicin distribution, independent of P-glycoprotein

GJ Schuurhuis
HJ Broxterman
J Lankelma
Research01 Nov 1991
British Journal of Cancer

Volume: 64, P: 857-861
Cyclosporin A and verapamil have different effects on energy metabolism in multidrug-resistant tumour cells

HJ Broxterman
HM Pinedo
J Lankelma
Research01 Jul 1990
British Journal of Cancer

Volume: 62, P: 85-88
Potent interaction of flavopiridol with MRP1

J H Hooijberg
H J Broxterman
HM Pinedo
ResearchOpen Access27 Aug 1999
British Journal of Cancer

Volume: 81, P: 269-276
The polyoxyethylene castor oil Cremophor EL modifies multidrug resistance

GJ Schuurhuis
HJ Broxterman
J Lankelma
Research01 Oct 1990
British Journal of Cancer

Volume: 62, P: 591-594
Do P-glycoprotein and major vault protein (MVP/LRP) expression correlate with in vitro daunorubicin resistance in acute myeloid leukemia?

HJ Broxterman
P Sonneveld
GJ Schuurhuis
Research05 Feb 1999
Leukemia

Volume: 13, P: 258-265
Role of MRP1 in multidrug resistance in acute myeloid leukemia

O Legrand
R Zittoun
J-P Marie
Research16 Apr 1999
Leukemia

Volume: 13, P: 578-584
In vitro biochemical and in vivo biological studies of the uridine 'rescue' of 5-fluorouracil

GJ Peters
J van Dijk
HM Pinedo
Research01 Mar 1988
British Journal of Cancer

Volume: 57, P: 259-265
Vinblastine and sulfinpyrazone export by the multidrug resistance protein MRP2 is associated with glutathione export

R Evers
M de Haas
P Borst
ResearchOpen Access04 Jul 2000
British Journal of Cancer

Volume: 83, P: 375-383
Reduced topoisomerase II activity in multidrug-resistant human non-small cell lung cancer cell lines

EWHM Eijdems
M de Haas
F Baas
Research01 Jan 1995
British Journal of Cancer

Volume: 71, P: 40-47
Activity of ‘Vitamin A-Acid’ in the Rat

J. F. ARENS
D. A. VAN DORP
Research02 Nov 1946
Nature

Volume: 158, P: 622-623
Multidrug resistance in acute leukemia: a comparison of different diagnostic methods

G Pall
M Spitaler
C Ludescher
Research01 Jul 1997
Leukemia

Volume: 11, P: 1067-1072
Role of the semi-quinone free radical of the anti-tumour agent etoposide (VP-16-213) in the inactivation of single- and double-stranded ΦX174 DNA

DRA Mans
J Retèl
J Lankelma
Research01 Jul 1990
British Journal of Cancer

Volume: 62, P: 54-60
Protection of cells from methotrexate toxicity by 7-hydroxymethotrexate

J M Gaukroger
L Wilson
Research01 Sept 1984
British Journal of Cancer

Volume: 50, P: 327-333
Multidrug resistance circumvention by a new triazinoaminopiperidine derivative S9788 in vitro: definition of the optimal schedule and comparison with verapamil

A-M Julia
H Roché
P Canal
Research01 May 1994
British Journal of Cancer

Volume: 69, P: 868-874
Expression of MDR1/P glycoprotein in human sarcomas

B Vergier
L Cany
JM Coindre
Research01 Dec 1993
British Journal of Cancer

Volume: 68, P: 1221-1226
Immunohistochemical detection of DNA topoisomerase IIα, P-glycoprotein and multidrug resistance protein (MRP) in small-cell and non-small-cell lung cancer

J Kreisholt
M Sorensen
M Sehested
Research01 May 1998
British Journal of Cancer

Volume: 77, P: 1469-1473
TOXICITY AND ANTITUMOR EFFECT OF 5-FLUOROURACIL (FU) 157 AND ITS RESCUE BY URIDINE (UR): 157

G J Peters
J Van Dijk
H M Pinedo
Research01 Jul 1985
Pediatric Research

Volume: 19, P: 770
Antibiotic-perturbed microbiota and the role of probiotics

In this Review, Szajewska, Scott and colleagues discuss the evidence for antibiotic-mediated perturbation of the gut microbiota and whether probiotics can help restore an antibiotic-disrupted microbiota.

Hania Szajewska
Karen P. Scott
Mary Ellen Sanders
Reviews11 Dec 2024
Nature Reviews Gastroenterology & Hepatology

Volume: 22, P: 155-172
Reduced cellular accumulation of topotecan: a novel mechanism of resistance in a human ovarian cancer cell line

J Ma
M Maliepaard
JHM Schellens
Research01 May 1998
British Journal of Cancer

Volume: 77, P: 1645-1652
Anthracycline subcellular distribution in human leukemic cells by microspectrofluorometry: factors contributing to drug-induced cell death and reversal of multidrug resistance

H Morjani
J-M Millot
M Manfait
Research01 Jul 1997
Leukemia

Volume: 11, P: 1170-1179
Comparison of ^99mTc-sestamibi and doxorubicin to monitor inhibition of P-glycoprotein function

T Muzzammil
M J Moore
J R Ballinger
ResearchOpen Access30 Jan 2001
British Journal of Cancer

Volume: 84, P: 367-373
CPT-11 sensitivity in relation to the expression of P170-glycoprotein and multidrug resistance-associated protein

WJM Jansen
TM Hulscher
E Boven
Research01 Feb 1998
British Journal of Cancer

Volume: 77, P: 359-365
ADENOSINE TRANSPORT BY ISOLATED RAT LIVER MITOCHONDRIA: 159

Keijo J Peuhkurinen
Albert R Collinson
John M Lowenstein
Research01 Jul 1985
Pediatric Research

Volume: 19, P: 770
The cytotoxic activity of Taxol in primary cultures of tumour cells from patients is partly mediated by Cremophor EL

P Nygren
K Csoka
R Larsson
Research01 Mar 1995
British Journal of Cancer

Volume: 71, P: 478-481
Prognostic role of clinical, pathological and biological characteristics in patients with locally advanced breast cancer

AH Honkoop
PJ van Diest
HM Pinedo
Research01 Feb 1998
British Journal of Cancer

Volume: 77, P: 621-626
Determinants of CPT-11 and SN-38 activities in human lung cancer cells

J van Ark-Otte
MA Kedde
G Giaccone
Research01 Jun 1998
British Journal of Cancer

Volume: 77, P: 2171-2176
Multidrug resistance phenotype in leukaemic cells from patients with acute myelocytic leukaemia can be detected with ⁹⁹Tc^m-MIBI

A Gruber
I Areström
H Jacobsson
Research01 Jun 1998
British Journal of Cancer

Volume: 77, P: 1732-1736
Fluoropyrimidine sensitivity of human MCF-7 breast cancer cells stably transfected with human uridine phosphorylase

P Cuq
C Rouquet
J-P Cano
ResearchOpen Access12 Jun 2001
British Journal of Cancer

Volume: 84, P: 1677-1680
The combined effects of IL-3 and PSC 833 on daunorubicin- and mitoxantrone cytotoxicity in two growth factor-dependent leukemic cell lines

J Asschert
E de Vries
E Vellenga
Research01 May 1997
Leukemia

Volume: 11, P: 680-686
Phase II trial of dexverapamil and epirubicin in patients with non-responsive metastatic breast cancer

M Lehnert
K Mross
H Kupper
Research01 Apr 1998
British Journal of Cancer

Volume: 77, P: 1155-1163
Flow cytometric analysis of P-glycoprotein function using rhodamine 123

J Pétriz
J García-López
Research01 Jul 1997
Leukemia

Volume: 11, P: 1124-1130
Multicentric evaluation of the MDR phenotype in leukemia

J-P Marie
S Huet
J Robert
Research01 Jul 1997
Leukemia

Volume: 11, P: 1086-1094
Multidrug resistance protein-mediated transport of chlorambucil and melphalan conjugated to glutathione

K Barnouin
I Leier
D Keppler
Research01 Jan 1998
British Journal of Cancer

Volume: 77, P: 201-209
Inhibitory effect of the reversal agents V-104, GF120918 and Pluronic L61 on MDR1 Pgp-, MRP1- and MRP2-mediated transport

R Evers
M Kool
P Borst
ResearchOpen Access04 Jul 2000
British Journal of Cancer

Volume: 83, P: 366-374
The acridonecarboxamide GF120918 potently reverses P-glycoprotein-mediated resistance in human sarcoma MES-Dx5 cells

H C L Traunecker
M C G Stevens
D R Ferry
ResearchOpen Access29 Oct 1999
British Journal of Cancer

Volume: 81, P: 942-951
The equilibrium and kinetic drug binding properties of the mouse P-gp1a and P-gp1b P-glycoproteins are similar

J C Taylor
D R Ferry
R Callaghan
ResearchOpen Access15 Oct 1999
British Journal of Cancer

Volume: 81, P: 783-789
The relationship between intrinsic thymidylate synthase expression and sensitivity to THYMITAQ^TM in human leukaemia and colorectal carcinoma cell lines

EJ Estlin
K Balmanno
GA Taylor
Research01 Dec 1997
British Journal of Cancer

Volume: 76, P: 1579-1585
Broad phase II and pharmacokinetic study of methoxy-morpholino doxorubicin (FCE 23762-MMRDX) in non-small-cell lung cancer, renal cancer and other solid tumour patients

M Bakker
JP Droz
EGE de Vries
Research01 Jan 1998
British Journal of Cancer

Volume: 77, P: 139-146
Idarubicin DNA intercalation is reduced by MRP1 and not Pgp

MEP Smeets
RAP Raymakers
TM de Witte
Research09 Sept 1999
Leukemia

Volume: 13, P: 1390-1398
BIRICODAR (VX-710; Incel™): an effective chemosensitizer in neuroblastoma

T Yanagisawa
A Newman
K Pritchard-Jones
ResearchOpen Access28 May 1999
British Journal of Cancer

Volume: 80, P: 1190-1196
In vivo efficacy of XR9051, a potent modulator of P-glycoprotein mediated multidrug resistance

P Mistry
J Plumb
P B Bevan
ResearchOpen Access12 Mar 1999
British Journal of Cancer

Volume: 79, P: 1672-1678
RETRACTED ARTICLE: Effect of pantoprazole to enhance activity of docetaxel against human tumour xenografts by inhibiting autophagy

Q Tan
A M Joshua
I F Tannock
ResearchOpen Access03 Feb 2015
British Journal of Cancer

Volume: 112, P: 832-840
P-glycoprotein in primary acute myeloid leukemia and treatment outcome of idarubicin/cytosine arabinoside-based induction therapy

HJ Broxterman
P Sonneveld
GJ Schuurhuis
Research06 Jun 2000
Leukemia

Volume: 14, P: 1018-1024
Control of MAPK signalling: from complexity to what really matters

Jorrit J Hornberg
Bernd Binder
Hans V Westerhoff
Research20 Jun 2005
Oncogene

Volume: 24, P: 5533-5542