Nature Search

The large E1B protein together with the E4orf6 protein target p53 for active degradation in adenovirus infected cells

Wilma T Steegenga
Nicole Riteco
Johannes L Bos
Research26 Jan 1998
Oncogene

Volume: 16, P: 349-357
Roozeboom's Solid Solution Diagram, Type II

J. TIMMERMANS
Research01 Jul 1944
Nature

Volume: 154, P: 23-24
Correlation between 5-fluorouracil metabolism and treatment response in two variants of C26 murine colon carcinoma

Y J L Kamm
G J Peters
A Heerschap
ResearchOpen Access12 Aug 2003
British Journal of Cancer

Volume: 89, P: 754-762
Gated binding of ligands to proteins

J. Andrew McCammon
Scott H. Northrup
Research24 Sept 1981
Nature

Volume: 293, P: 316-317
SETBP1 variants outside the degron disrupt DNA-binding, transcription and neuronal differentiation capacity to cause a heterogeneous neurodevelopmental disorder

Different types of SETBP1 variants cause variable developmental syndromes with only partial clinical and functional overlaps. Here, the authors report that SETBP1 variants outside the degron region impair DNA-binding, transcription, and neuronal differentiation capacity and morphologies.

Maggie M. K. Wong
Rosalie A. Kampen
Simon E. Fisher
ResearchOpen Access10 Oct 2025
Nature Communications

Volume: 16, P: 1-23
Forage Crops for Soiling, Silage, Hay and Pasture

E. J. R.
Books & Arts27 Feb 1908
Nature

Volume: 77, P: 388-389
Primary structure of C-terminal functional sites in ovine rhodopsin

John B. C. Findlay
Michael Brett
Darryl J. C. Pappin
Research24 Sept 1981
Nature

Volume: 293, P: 314-316
Author Correction: Regulatory T cells in psoriatic arthritis: an IL-17A-producing, Foxp3^intCD161 + RORγt + ICOS + phenotype, that associates with the presence of ADAMTSL5 autoantibodies

Juliëtte N. Pouw
Michel A. M. Olde Nordkamp
Marianne Boes
Amendments and CorrectionsOpen Access24 Jan 2023
Scientific Reports

Volume: 13, P: 1
Uteroverdin

B. LEMBERG
J. BARCROFT
D. KEILIN
Research05 Dec 1931
Nature

Volume: 128, P: 967-968
Structural and physical investigation of ordered BaO-deficient Ba₃PuO₆

The exact crystal chemistry of perovskites containing 5f elements has remained a matter of debate. Here, the authors synthesise a BaO-deficient Pu-based perovskite with a composition close to Ba3PuO6 and study the Pu oxidation state, the crystal structure and Ba/Pu ratio, reporting on thermodynamic and magnetic properties and offering new insights into Ba-Pu-O solid-state chemistry.

Andries van Hattem
Karin Popa
Rudy J. M. Konings
ResearchOpen Access01 Sept 2025
Communications Chemistry

Volume: 8, P: 1-12
Local halide heterogeneity drives surface wrinkling in mixed-halide wide-bandgap perovskites

Surface wrinkling reduces the performance of mixed-halide perovskite solar cells. Here, the authors identify that sequential nucleation of bromide-rich and iodide-rich domains results in compositional heterogeneity and subsequent wrinkling.

Kunal Datta
Simone C. W. van Laar
René A. J. Janssen
ResearchOpen Access25 Feb 2025
Nature Communications

Volume: 16, P: 1-13
Membranes with artificial free-volume for biofuel production

The free-volume of a polymer is a key parameter in its ability to permit through transport of small molecules. Here, the authors develop a way of introducing different degrees of artificial free-volume to a polymer membrane, and thus tailor its penetrability for applications including biofuel purification.

Nikos Petzetakis
Cara M. Doherty
Nitash P. Balsara
ResearchOpen Access24 Jun 2015
Nature Communications

Volume: 6, P: 1-8
Persistent DNA damage induced by ultraviolet light inhibits p21^waf1 and bax expression: implications for DNA repair, UV sensitivity and the induction of apoptosis

Bruce C McKay
Mats Ljungman
Andrew J Rainbow
Research10 Aug 1998
Oncogene

Volume: 17, P: 545-555
How Human Electrophysiology Informs Psychopharmacology: from Bottom-up Driven Processing to Top-Down Control

J Leon Kenemans
Seppo Kähkönen
Reviews06 Oct 2010
Neuropsychopharmacology

Volume: 36, P: 26-51
A multicenter longitudinal study of cholinergic subgroups in Parkinson disease

In a two-center longitudinal study, the authors present evidence in support of cholinergic system subgroups in Parkinson’s disease (PD), which exhibit both downregulation and upregulation of signaling. Subgroup-specific cholinergic changes associated with clinical PD features.

Nicolaas I. Bohnen
Stiven Roytman
Prabesh Kanel
ResearchOpen Access01 Jul 2025
Nature Communications

Volume: 16, P: 1-14
Prof. T. M. Lowry, C.B.E., F.R.S.

WM. J. POPE
Comments & Opinion28 Nov 1936
Nature

Volume: 138, P: 912-913
Correction: Corrigendum: Genome-wide association study of systemic sclerosis identifies CD247 as a new susceptibility locus

Timothy R D J Radstake
Olga Gorlova
Maureen D Mayes
Amendments and Corrections27 Apr 2011
Nature Genetics

Volume: 43, P: 499
Identification of a non-canonical chemokine-receptor pathway suppressing regulatory T cells to drive atherosclerosis

Döring, van der Vorst, Yan, Neideck et al. present a non-canonical chemokine pathway involving CCL17 signaling through CCR8, which induces CCL3 expression independent of CCR4 and suppresses the functions of atheroprotective T_reg cells.

Yvonne Döring
Emiel P. C. van der Vorst
Christian Weber
ResearchOpen Access22 Jan 2024
Nature Cardiovascular Research

Volume: 3, P: 221-242
Pathogenic SPTBN1 variants cause an autosomal dominant neurodevelopmental syndrome

SPTBN1 mutations cause a neurodevelopmental syndrome characterized by intellectual disability, language and motor delays, autism, seizures and other features. The variants disrupt βII-spectrin function and disturb cytoskeletal organization and dynamics.

Margot A. Cousin
Blake A. Creighton
Damaris N. Lorenzo
Research01 Jul 2021
Nature Genetics

Volume: 53, P: 1006-1021
Age-related mitochondrial alterations in brain and skeletal muscle of the YAC128 model of Huntington disease

Kristina Bečanović
Muhammad Asghar
Blair R. Leavitt
ResearchOpen Access14 Oct 2021
npj Aging and Mechanisms of Disease

Volume: 7, P: 1-14
Lack of evidence for a causal role of CALR3 in monogenic cardiomyopathy

Judith M. A. Verhagen
Job H. Veldman
Ingrid M. B. H. van de Laar
ResearchOpen Access09 Jul 2018
European Journal of Human Genetics

Volume: 26, P: 1603-1610
Induction of ATF3 by ionizing radiation is mediated via a signaling pathway that includes ATM, Nibrin1, stress-induced MAPkinases and ATF-2

Jaap Kool
Mohamed Hamdi
Hans van Dam
Research02 Jul 2003
Oncogene

Volume: 22, P: 4235-4242
The future of autologous stem cell transplantation in systemic sclerosis

Autologous haematopoietic stem cell transplantation revolutionized the treatment of severe systemic sclerosis as the first therapy able to induce long-term remission in this relentlessly fibrosing disease. Nevertheless, questions remain about patient selection, conditioning, and how this treatment fits into the evolving immune-modifying therapeutic landscape. The field should move beyond standardization towards precision therapy.

Charlotte Schimmel
Julia Spierings
Comments & Opinion09 Dec 2025
Nature Reviews Rheumatology

P: 1-2
Mutations in SMAD3 cause a syndromic form of aortic aneurysms and dissections with early-onset osteoarthritis

Aida Bertoli-Avella and colleagues report the identification of SMAD3 mutations in individuals with a syndromic form of aortic aneurysms and dissections with early-onset osteoarthritis. The mutations cause increased aortic expression of components of the TGF-β signaling pathway.

Ingrid M B H van de Laar
Rogier A Oldenburg
Aida M Bertoli-Avella
Research09 Jan 2011
Nature Genetics

Volume: 43, P: 121-126
Thermodynamics and Fluids

J. M. COULSON
Books & Arts27 Sept 1958
Nature

Volume: 182, P: 822-823
Drugs and the Brain

H. J. EYSENCK
Books & Arts27 Sept 1958
Nature

Volume: 182, P: 823
Modelling cholinergic and dopaminergic function over time in Parkinson’s disease with and without GBA1 variants

Sofie Slingerland
Eline K. R. de Meyer
Teus van Laar
ResearchOpen Access12 Nov 2025
npj Parkinson's Disease

Volume: 11, P: 1-10
Adult orbital xanthogranuloma: long-term follow-up of treated cases

S. E. Detiger
G. J. Hötte
D. Paridaens
Research16 Dec 2022
Eye

Volume: 37, P: 2475-2481
Neuroimmune cardiovascular interfaces control atherosclerosis

The peripheral nervous system uses neuroimmune cardiovascular interfaces to assemble a structural artery–brain circuit, and therapeutic intervention in the artery–brain circuit attenuates atherosclerosis.

Sarajo K. Mohanta
Li Peng
Andreas J. R. Habenicht
Research27 Apr 2022
Nature

Volume: 605, P: 152-159
Regulated IRE1-dependent mRNA decay sets the threshold for dendritic cell survival

Tavernier et al. show that loss of the protective IRE1–XBP1 stress sensor results in the death of conventional dendritic cells in the lung, whereas those in the intestine survive due to a stronger ATF4-dependent stress response and RIDD activation.

Simon J. Tavernier
Fabiola Osorio
Sophie Janssens
Research01 May 2017
Nature Cell Biology

Volume: 19, P: 698-710
Governance and resilience as entry points for transforming food systems in the countdown to 2030

This study presents the first annual update of the indicator framework developed by the Food Systems Countdown Initiative, published in Nature Food in 2023. Almost half of all indicators show some desirable trends. Governance and resilience indicators were revealed as the most connected across themes, constituting entry points for transformative change.

Kate R. Schneider
Roseline Remans
Jessica Fanzo
ResearchOpen Access14 Jan 2025
Nature Food

Volume: 6, P: 105-116
Clinical utility of DNA-methylation signatures in routine diagnostics for neurodevelopmental disorders

Daphne J. Smits
Christophe Debuy
Tahsin Stefan Barakat
Research29 Jul 2025
European Journal of Human Genetics

Volume: 33, P: 1281-1289
Quantifying thermal adaptation of soil microbial respiration

Soil microbial respiration responses to warming have important implications for biogeochemical feedbacks. Here, using data from temperature gradients, the authors show that the rate of thermal adaptation of soil microbial respiration is lower than the rate of warming despite large community changes.

Charlotte J. Alster
Allycia van de Laar
Louis A. Schipper
ResearchOpen Access06 Sept 2023
Nature Communications

Volume: 14, P: 1-12
Potentiation of a recombinant oncolytic parvovirus by expression of Apoptin

Sharon Olijslagers
Alexandra Y Dege
Jan J Cornelis
Research21 Dec 2001
Cancer Gene Therapy

Volume: 8, P: 958-965
Fecal microbiome alterations in treatment-naive de novo Parkinson’s disease

Jeffrey M. Boertien
Kirsi Murtomäki
T. van Laar
ResearchOpen Access10 Oct 2022
npj Parkinson's Disease

Volume: 8, P: 1-12
Antibodies against citrullinated proteins: which test is best?

Jacob M van Laar
Comments & Opinion01 Dec 2006
Nature Clinical Practice Rheumatology

Volume: 2, P: 652-653
Slow unloading leads to DNA-bound β₂-sliding clamp accumulation in live Escherichia coli cells

DNA replication is accomplished by the replisome, a multi-protein complex that comprises the sliding clamp. Here, Moolman et al. present quantitative and dynamic measurements of the number of β₂-sliding clamps at the single-cell level in live E. colicells to shed light on key aspects of DNA replication.

M. Charl Moolman
Sriram Tiruvadi Krishnan
Nynke H. Dekker
ResearchOpen Access18 Dec 2014
Nature Communications

Volume: 5, P: 1-11
Regulatory T cells in psoriatic arthritis: an IL-17A-producing, Foxp3^intCD161 + RORγt + ICOS + phenotype, that associates with the presence of ADAMTSL5 autoantibodies

Juliëtte N. Pouw
Michel A. M. Olde Nordkamp
Marianne Boes
ResearchOpen Access30 Nov 2022
Scientific Reports

Volume: 12, P: 1-14
Cell-specific and divergent roles of the CD40L-CD40 axis in atherosclerotic vascular disease

Previous studies have shown that the CD40L-CD40 signaling axis plays a role in atherosclerosis. Here the authors investigate the cell-specific functions of the most relevant CD40L-expressing cell types in atherosclerosis. Deficiency of T cell-derived CD40L reduces and stabilizes plaques through impaired Th1 polarization while platelet-derived CD40L ameliorates atherothrombosis.

Michael Lacy
Christina Bürger
Esther Lutgens
ResearchOpen Access18 Jun 2021
Nature Communications

Volume: 12, P: 1-12
Measuring fatigue in rheumatoid arthritis

Irksome to debilitating, fatigue is a frequent symptom of rheumatoid arthritis (RA). Patients regard it as an important, neglected facet of the disease. An analysis of the effect of biologic therapies on fatigue has yielded disappointing results—do current treatments lack efficacy, or are we failing to measure adequate parameters?

Stephanie Nikolaus
Mart A. F. J. van de Laar
News & Views30 Aug 2011
Nature Reviews Rheumatology

Volume: 7, P: 562-564
Nucleosomes and systemic sclerosis

Systemic sclerosis (SSc) is characterized by an abnormal immune response to innocuous antigens that might lead to autoantibody production. New observations suggest that nucleosomes can mediate both IgG production and B-cell proliferation, via Toll-like receptor signalling, and thereby affect the pathogenesis of SSc.

Steven O'Reilly
Jacob M. van Laar
News & Views04 Feb 2016
Nature Reviews Rheumatology

Volume: 12, P: 138-139
Genome-wide association study of systemic sclerosis identifies CD247 as a new susceptibility locus

Timothy Radstake and Maureen Mayes and colleagues report results of a genome-wide association study of systemic sclerosis. They identify a new susceptibility locus at CD247.

Timothy R D J Radstake
Olga Gorlova
Maureen D Mayes
Research11 Apr 2010
Nature Genetics

Volume: 42, P: 426-429
High quality of SARS-CoV-2 molecular diagnostics in a diverse laboratory landscape through supported benchmark testing and External Quality Assessment

John Sluimer
Willem M. R. van den Akker
Adam Meijer
ResearchOpen Access16 Jan 2024
Scientific Reports

Volume: 14, P: 1-12
Lithogenesis der Gegenwart. Beobachtungen über die Bildung der Gesteine an der heutigen Erdoberfläche. Dritter Theil einer Einleitung in die Geologie als historische Wissenschaft. Geotektonische Probleme. Morphologie der Erdoberfläche

J. W. GREGORY
Books & Arts31 Jan 1895
Nature

Volume: 51, P: 313-317
Digital competence in adolescents and young adults: a critical analysis of concomitant variables, methodologies and intervention strategies

Annika Kreuder
Ulrich Frick
Sabine J. Schlittmeier
ReviewsOpen Access04 Jan 2024
Humanities and Social Sciences Communications

Volume: 11, P: 1-20
Transient exposure to rotenone causes degeneration and progressive parkinsonian motor deficits, neuroinflammation, and synucleinopathy

Amber D. Van Laar
Katherine R. Webb
Emily M. Rocha
ResearchOpen Access11 Aug 2023
npj Parkinson's Disease

Volume: 9, P: 1-9
The state of food systems worldwide in the countdown to 2030

Holistic indicator frameworks are needed to track food systems transformation. This Analysis shows the application of a framework recently developed by the Food Systems Countdown Initiative to all UN member states, revealing current status, data gaps and priority actions.

Kate R. Schneider
Jessica Fanzo
Keith Wiebe
ResearchOpen Access19 Dec 2023
Nature Food

Volume: 4, P: 1090-1110
Genetics of rheumatoid arthritis contributes to biology and drug discovery

A genome-wide association study meta-analysis of more than 100,000 subjects of European and Asian ancestries reveals 42 new risk loci for rheumatoid arthritis, with follow-up studies identifying 98 biological candidate genes that are either already being targeted by drugs or could be in the future.

Yukinori Okada
Di Wu
Robert M. Plenge
Research25 Dec 2013
Nature

Volume: 506, P: 376-381
Does referral to specialist paediatric palliative care services reduce hospital admissions in oncology patients at the end of life?

L K Fraser
M van Laar
R G Feltbower
ResearchOpen Access28 Feb 2013
British Journal of Cancer

Volume: 108, P: 1273-1279
DLG4-related synaptopathy: a new rare brain disorder

Agustí Rodríguez-Palmero
Melissa Maria Boerrigter
Zeynep Tümer
Research17 Feb 2021
Genetics in Medicine

Volume: 23, P: 888-899

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