Advanced search

Filter By:

Journal Check one or more journals to show results from those journals only.

Choose more journals

Article type Check one or more article types to show results from those article types only.
Subject Check one or more subjects to show results from those subjects only.
Date Choose a date option to show results from those dates only.

Custom date range

Clear all filters
Sort by:
Showing 1–9 of 9 results
Advanced filters: Author: J. Ablaeva Clear advanced filters

  • Analysis of the longest-lived mammal, the bowhead whale, reveals an improved ability to repair DNA breaks, mediated by high levels of cold-inducible RNA-binding protein.   

    • Denis Firsanov
    • Max Zacher
    • Vera Gorbunova
    ResearchOpen Access
    Nature
    Volume: 648, P: 717-725

  • Blind mole rats are small rodents characterized by an exceptionally long lifespan and resistance to both spontaneous and induced tumorigenesis. Gorbunova and colleagues show that a transposon-triggered innate immune response confers cancer resistance to the blind mole rat.

    • Yang Zhao
    • Ena Oreskovic
    • Vera Gorbunova
    Research
    Nature Immunology
    Volume: 22, P: 1219-1230

  • Mice overexpressing Has2 from the naked mole-rat showed an increase in hyaluronan levels in several tissues, and a lower incidence of spontaneous and induced cancer, attenuated inflammation through several pathways, extended lifespan and improved healthspan.

    • Zhihui Zhang
    • Xiao Tian
    • Vera Gorbunova
    Research
    Nature
    Volume: 621, P: 196-205

  • The exceptionally long-lived naked mole-rat is characterized by the lack of increased mortality with aging. Here the authors perform epigenetic studies to show that naked mole-rats epigenetically age despite their non-increasing mortality rate.

    • Csaba Kerepesi
    • Margarita V. Meer
    • Vadim N. Gladyshev
    ResearchOpen Access
    Nature Communications
    Volume: 13, P: 1-10

  • Hyaluronic acid is believed to plays a critical role in cancer resistance and longevity of the naked mole rat. Here, Zhao and colleagues show that accumulation of high levels of hyaluronic acid has co-evolved repeatedly in mammalian clades with adaptation to subterranean habitats.

    • Yang Zhao
    • Zhizhong Zheng
    • Vera Gorbunova
    ResearchOpen Access
    Nature Communications
    Volume: 14, P: 1-18

  • This study identifies and characterizes evolutionarily conserved cytosine methylation patterns related to age across mammals and establishes pan-mammalian epigenetic clocks.

    • A. T. Lu
    • Z. Fei
    • S. Horvath
    ResearchOpen Access
    Nature Aging
    Volume: 3, P: 1144-1166

  • Cancer incidence is rare in long-lived bats. Here the authors find that although bat fibroblasts express telomerase and require only two oncogenic hits for malignant transformation, bats may rely on elevated p53 signaling and enhanced immunosurveillance to prevent cancer.

    • Fathima Athar
    • Zhizhong Zheng
    • Vera Gorbunova
    ResearchOpen Access
    Nature Communications
    Volume: 16, P: 1-16