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Showing 1–7 of 7 results
Advanced filters: Author: J. Biteau Clear advanced filters
  • This directory was made possible by a unique international collaboration between the 633 scientists whose names appear below. It represents both the first published description of the complete sequence of most chromsomes from Saccharomyces cerevisiae, and the first published overview of the entire sequence. As such, the authors would like future papers referring to the entire sequence and/or its contents to cite this directory; future papers referring to the sequence of individual chromosomes should refer to the papers listed at the head of page 9. The authors’ affiliations appear in the papers describing the individual chromosomes.

    • A. Goffeau
    • R. Aert
    • E. Zumstein
    Editorial
    Nature
    Volume: 387, P: 5
  • The complete DNA sequence of the yeast Saccharomyces cerevisiae chromosome IV has been determined. Apart from chromosome XII, which contains the 1–2 Mb rDNA cluster, chromosome IV is the longest S. cerevisiae chromosome. It was split into three parts, which were sequenced by a consortium from the European Community, the Sanger Centre, and groups from St Louis and Stanford in the United States. The sequence of 1,531,974 base pairs contains 796 predicted or known genes, 318 (39.9%) of which have been previously identified. Of the 478 new genes, 225 (28.3%) are homologous to previously identified genes and 253 (32%) have unknown functions or correspond to spurious open reading frames (ORFs). On average there is one gene approximately every two kilobases. Superimposed on alternating regional variations in G+C composition, there is a large central domain with a lower G+C content that contains all the yeast transposon (Ty) elements and most of the tRNA genes. Chromosome IV shares with chromosomes II, V, XII, XIII and XV some long clustered duplications which partly explain its origin.

    • C. Jacq
    • J. Alt-Mörbe
    • P. Zaccaria
    Research
    Nature
    Volume: 387, P: 75-78
  • A recent survey suggests that reducing the number of meetings and conferences is a viable way to address concerns about the effectiveness of the modern scientific collaboration process, its effects on the environment and the well-being of the community.

    • L. Tibaldo
    • E. Prandini
    • A. Nelles
    Comments & Opinion
    Nature Astronomy
    Volume: 7, P: 1408-1411
  • Extreme blazars emitting teraelectronvolt photons are ideal targets to study particle acceleration processes. The growing number of such sources has been critical for γ-ray cosmology, studying intergalactic magnetic fields and putting constraints on exotic physics.

    • J. Biteau
    • E. Prandini
    • A. Zech
    Reviews
    Nature Astronomy
    Volume: 4, P: 124-131