One of four papers establishing certain PHD domains as effectors of trimethylated histone H3K4, a chromatin mark generally associated with active transcription. This paper shows that the interaction of H3K4me3 with the PHD finger of an ATP-dependent chromatin remodelling complex is involved in control of Hox gene expression during Xenopus development.
- Joanna Wysocka
- Tomek Swigut
- C. David Allis
