Nature Search

Synergy between culturomics and metagenomics of health status-associated gut bacteria originating from non-IBD and IBD populations

N. Plomp
R. Gacesa
H. J. M. Harmsen
ResearchOpen Access27 Nov 2025
Scientific Reports

Volume: 15, P: 1-14
Optimized whole-genome sequencing workflow for tumor diagnostics in routine pathology practice

This protocol presents a comprehensive workflow for the implementation of whole-genome sequencing in routine tumor diagnostics, exemplified by the pipeline used in the Netherlands Cancer Institute.

Kris G. Samsom
Linda J. W. Bosch
Kim Monkhorst
Protocols13 Dec 2023
Nature Protocols

Volume: 19, P: 700-726
204 ADAPTIVE RESPONSE OF VLBW INFANTS TO INDWELLING NASOGASTRIC TUBE (NGT)

P Sasidharan
D Billman
J Bamberger
Research01 Jul 1994
Pediatric Research

Volume: 36, P: 36
Duplication of the IL2RA locus causes excessive IL-2 signaling and may predispose to very early onset colitis

Maria E. Joosse
Fabienne Charbit-Henrion
Janneke N. Samsom
ResearchOpen Access05 Jul 2021
Mucosal Immunology

Volume: 14, P: 1172-1182
TGFβR signalling controls CD103⁺CD11b⁺ dendritic cell development in the intestine

Developmental cues for the different dendritic cell (DC) subsets in the intestine are yet to be defined. Here the authors show that TGFβR1 signalling is needed for development of CD103⁺CD11b⁺ intestinal DCs from CD103⁻CD11b⁺ cells and that they contribute to the generation of Th17 and regulatory T cells

C. C. Bain
J. Montgomery
A. McI. Mowat
ResearchOpen Access20 Sept 2017
Nature Communications

Volume: 8, P: 1-12
Increased production of interleukin-21, but not interleukin-17A, in the small intestine characterizes pediatric celiac disease

M A van Leeuwen
D J Lindenbergh-Kortleve
J N Samsom
Research10 Apr 2013
Mucosal Immunology

Volume: 6, P: 1202-1213
Lipid Profile and Carotid Intima-Media Thickness in a Prospective Cohort of Very Preterm Subjects at Age 19 Years: Effects of Early Growth and Current Body Composition

Martijn J J Finken
Akin Inderson
Jan M Wit
Research01 Apr 2006
Pediatric Research

Volume: 59, P: 604-609
IL-10 signaling prevents gluten-dependent intraepithelial CD4⁺ cytotoxic T lymphocyte infiltration and epithelial damage in the small intestine

L. M. M. Costes
D. J. Lindenbergh-Kortleve
J. N. Samsom
Research12 Dec 2018
Mucosal Immunology

Volume: 12, P: 479-490
Human fetal lymphoid tissue–inducer cells are interleukin 17–producing precursors to RORC⁺ CD127⁺ natural killer–like cells

Mouse lymphoid tissue–inducer (LTi) cells require the transcription factor RORγt. Cupedo's group identifies RORγt⁺ human LTi cell equivalents as committed natural killer cell precursors, and teams led by Vivier and Diefenbach describe RORγt-expressing interleukin 22–producing natural killer cells in mouse gut.

Tom Cupedo
Natasha K Crellin
Hergen Spits
Research23 Nov 2008
Nature Immunology

Volume: 10, P: 66-74
IL-10 signaling in dendritic cells controls IL-1β-mediated IFNγ secretion by human CD4⁺ T cells: relevance to inflammatory bowel disease

S. Veenbergen
P. Li
J. N. Samsom
Research15 Aug 2019
Mucosal Immunology

Volume: 12, P: 1201-1211
Frequencies of circulating regulatory TIGIT⁺CD38⁺ effector T cells correlate with the course of inflammatory bowel disease

Maria E. Joosse
Celia L. Menckeberg
Janneke N. Samsom
Research20 Aug 2018
Mucosal Immunology

Volume: 12, P: 154-163
Faecalibacterium prausnitzii A2-165 has a high capacity to induce IL-10 in human and murine dendritic cells and modulates T cell responses

Oriana Rossi
Lisette A. van Berkel
Jerry M. Wells
ResearchOpen Access04 Jan 2016
Scientific Reports

Volume: 6, P: 1-12
Macrophage-mediated gliadin degradation and concomitant IL-27 production drive IL-10- and IFN-γ-secreting Tr1-like-cell differentiation in a murine model for gluten tolerance

M A van Leeuwen
L M M Costes
J N Samsom
Research31 Aug 2016
Mucosal Immunology

Volume: 10, P: 635-649
High expression of secretory leukocyte protease inhibitor (SLPI) in stage III micro-satellite stable colorectal cancer is associated with reduced disease recurrence

Sandrine Nugteren
Sjoerd H. den Uil
Janneke N. Samsom
ResearchOpen Access16 Jul 2022
Scientific Reports

Volume: 12, P: 1-10
Cyclooxygenase-2 in mucosal DC mediates induction of regulatory T cells in the intestine through suppression of IL-4

F Broere
M F du Pré
J N Samsom
Research04 Mar 2009
Mucosal Immunology

Volume: 2, P: 254-264
Activation of NF-κB driven inflammatory programs in mesenchymal elements attenuates hematopoiesis in low-risk myelodysplastic syndromes

Zhen Ping
Si Chen
Marc H. G. P. Raaijmakers
ResearchOpen Access12 Oct 2018
Leukemia

Volume: 33, P: 536-541
Proteomic analyses do not reveal subclinical inflammation in fatigued patients with clinically quiescent inflammatory bowel disease

Arno R. Bourgonje
Sietse J. Wichers
Lieke M. Spekhorst
ResearchOpen Access26 Aug 2022
Scientific Reports

Volume: 12, P: 1-11
Serum amyloid P component (SAP) modulates antidepressant effects through promoting membrane insertion of the serotonin transporter

Ping Su
Shuxin Yan
Fang Liu
Research08 Sept 2022
Neuropsychopharmacology

Volume: 48, P: 508-517
Differences in Behavioral Outcome and Motor Development at School Age After Neonatal Treatment for Chronic Lung Disease with Dexamethasone versus Hydrocortisone

Rosa Karemaker
Cobi J Heijnen
Frank van Bel
Research01 Dec 2006
Pediatric Research

Volume: 60, P: 745-750
Temporal and spatial interplay of microbiota and intestinal mucosa drive establishment of immune homeostasis in conventionalized mice

Sahar El Aidy
Peter van Baarlen
Michiel Kleerebezem
Research23 May 2012
Mucosal Immunology

Volume: 5, P: 567-579
Genomic analysis of early-stage lung cancer reveals a role for TP53 mutations in distant metastasis

Debra Van Egeren
Khushi Kohli
Zenta Walther
ResearchOpen Access09 Nov 2022
Scientific Reports

Volume: 12, P: 1-6
Colonic tolerance develops in the iliac lymph nodes and can be established independent of CD103⁺ dendritic cells

S Veenbergen
L A van Berkel
J N Samsom
Research18 Nov 2015
Mucosal Immunology

Volume: 9, P: 894-906
Growth pattern and final height of very preterm vs. very low birth weight infants

Jonneke J Hollanders
Sylvia M van der Pal
Martijn J J Finken
Research31 May 2017
Pediatric Research

Volume: 82, P: 317-323
Tipping the balance: inhibitory checkpoints in intestinal homeostasis

Maria E. Joosse
Iris Nederlof
Janneke N. Samsom
Reviews29 Nov 2018
Mucosal Immunology

Volume: 12, P: 21-35

Search

Synergy between culturomics and metagenomics of health status-associated gut bacteria originating from non-IBD and IBD populations

Optimized whole-genome sequencing workflow for tumor diagnostics in routine pathology practice

204 ADAPTIVE RESPONSE OF VLBW INFANTS TO INDWELLING NASOGASTRIC TUBE (NGT)

Duplication of the IL2RA locus causes excessive IL-2 signaling and may predispose to very early onset colitis

TGFβR signalling controls CD103⁺CD11b⁺ dendritic cell development in the intestine

Increased production of interleukin-21, but not interleukin-17A, in the small intestine characterizes pediatric celiac disease

Lipid Profile and Carotid Intima-Media Thickness in a Prospective Cohort of Very Preterm Subjects at Age 19 Years: Effects of Early Growth and Current Body Composition

IL-10 signaling prevents gluten-dependent intraepithelial CD4⁺ cytotoxic T lymphocyte infiltration and epithelial damage in the small intestine

Human fetal lymphoid tissue–inducer cells are interleukin 17–producing precursors to RORC⁺ CD127⁺ natural killer–like cells

IL-10 signaling in dendritic cells controls IL-1β-mediated IFNγ secretion by human CD4⁺ T cells: relevance to inflammatory bowel disease

Frequencies of circulating regulatory TIGIT⁺CD38⁺ effector T cells correlate with the course of inflammatory bowel disease

Faecalibacterium prausnitzii A2-165 has a high capacity to induce IL-10 in human and murine dendritic cells and modulates T cell responses

Macrophage-mediated gliadin degradation and concomitant IL-27 production drive IL-10- and IFN-γ-secreting Tr1-like-cell differentiation in a murine model for gluten tolerance

High expression of secretory leukocyte protease inhibitor (SLPI) in stage III micro-satellite stable colorectal cancer is associated with reduced disease recurrence

Cyclooxygenase-2 in mucosal DC mediates induction of regulatory T cells in the intestine through suppression of IL-4

Activation of NF-κB driven inflammatory programs in mesenchymal elements attenuates hematopoiesis in low-risk myelodysplastic syndromes

Proteomic analyses do not reveal subclinical inflammation in fatigued patients with clinically quiescent inflammatory bowel disease

Serum amyloid P component (SAP) modulates antidepressant effects through promoting membrane insertion of the serotonin transporter

Differences in Behavioral Outcome and Motor Development at School Age After Neonatal Treatment for Chronic Lung Disease with Dexamethasone versus Hydrocortisone

Temporal and spatial interplay of microbiota and intestinal mucosa drive establishment of immune homeostasis in conventionalized mice

Genomic analysis of early-stage lung cancer reveals a role for TP53 mutations in distant metastasis

Colonic tolerance develops in the iliac lymph nodes and can be established independent of CD103⁺ dendritic cells

Growth pattern and final height of very preterm vs. very low birth weight infants

Tipping the balance: inhibitory checkpoints in intestinal homeostasis

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