In a series of Huntington’s disease (HD) brains, the authors identified phospho-tau aggregation in all cases. In contrast to recent observations suggesting a new role for tau in HD pathogenesis, the tau pathology in our cases was classifiable into known diagnostic entities and most likely represents non-specific age- or perhaps trauma-related changes.
- Swikrity Upadhyay Baskota
- Oscar L. Lopez
- Julia Kofler