This Review summarizes the process involved in the metabolism of macronutrients (carbohydrates, lipids and proteins) with a focus on the physiological and neuroendocrine aspects. The associations between macronutrients and obesity are also discussed in the context of factors such as genetics and the microbiome composition.
- Rodrigo San-Cristobal
- Santiago Navas-Carretero
- José Alfredo Martínez