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Advanced filters: Author: Jack D. Duryea Clear advanced filters

  • AgRP neurons in the hypothalamic arcuate nucleus (ARH) are involved in regulating hunger and energy balance. Here the authors show that knockout of the DNA methyltransferase Dnmt3a in AgRP neurons of the ARH leads to a reduction in voluntary exercise along with numerous epigenetic and gene expression changes in ARH neurons.

    • Harry MacKay
    • C. Anthony Scott
    • Robert A. Waterland
    ResearchOpen Access
    Nature Communications
    Volume: 10, P: 1-11