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Showing 1–2 of 2 results
Advanced filters: Author: Jack H. Landmann Clear advanced filters

  • One of three back-to-back papers to show that dosage of BACH2 can modulate T cell differentiation and function and how we might apply this to enhance CAR T cell therapies for cancer.

    • Tien-Ching Chang
    • Amanda Heard
    • Nathan Singh
    Research
    Nature Immunology
    P: 1-12

  • Loss of surface CD19 expression by leukemic cells leads to resistance and relapse to CD19-targeted CAR-T therapies. Here the authors show that loss of SPPL3 in malignant B cells results in hyperglycosylation of CD19.

    • Amanda Heard
    • Jack H. Landmann
    • Nathan Singh
    ResearchOpen Access
    Nature Communications
    Volume: 13, P: 1-11