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Showing 1–2 of 2 results
Advanced filters: Author: Jacob A. Zahm Clear advanced filters

  • NMR shows that ATP- and ADP-actin differ globally, including ground and excited state structures and dynamic architecture. Analyses of an actin mutant suggest the high-energy conformer of ATP-actin may be on the pathway to filament nucleation.

    • Rustam Ali
    • Jacob A. Zahm
    • Michael K. Rosen
    ResearchOpen Access
    Nature Structural & Molecular Biology
    Volume: 29, P: 320-328

  • Plasmodium parasites use Duffy-binding proteins (DBPs) to invade erythrocyte precursor cells via binding to host protein DARC. Now this interaction is examined by structural and functional work on Plasmodium vivax DBP, revealing that it binds to DARC as a dimer and providing insights into host protective responses and immune evasion by the parasite.

    • Joseph D Batchelor
    • Jacob A Zahm
    • Niraj H Tolia
    Research
    Nature Structural & Molecular Biology
    Volume: 18, P: 908-914