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Showing 1–3 of 3 results
Advanced filters: Author: Jacobus Burggraaf Clear advanced filters

  • Iatrogenic injury of the ureters is a feared complication of laparoscopic abdominal surgery. Here the authors present the NIR fluorophore ZW800-1 as an intraoperative imaging agent for ureter mapping, showing its safety, pharmacokinetic properties, and efficacy in healthy volunteers and patients undergoing abdominopelvic surgery.

    • Kim S. de Valk
    • Henricus J. Handgraaf
    • Alexander L. Vahrmeijer
    ResearchOpen Access
    Nature Communications
    Volume: 10, P: 1-6

  • Fluorescence-guided surgery (FGS) using tumour-targeted imaging agents has emerged over the past decade as a method of intraoperative cancer detection; however, the clinical implementation of tumour-targeted FGS remains in the early stages. The authors of this Review discuss how target selection, imaging agents and detection systems could enable real-time intraoperative visualization to benefit patients with cancer.

    • J. Sven D. Mieog
    • Friso B. Achterberg
    • Alexander L. Vahrmeijer
    Reviews
    Nature Reviews Clinical Oncology
    Volume: 19, P: 9-22