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Advanced filters: Author: Jaden Y. Fang Clear advanced filters

m³C32 tRNA modification controls serine codon-biased mRNA translation, cell cycle, and DNA-damage response

Here the authors define METTL2A/2B/6-dependent m³C tRNA modification in human cells and uncover a particular requirement of m³C32 tRNA modification for serine codon-biased mRNA translation of cell cycle, and DNA repair genes.

Jia Cui
Erdem Sendinc
Richard I. Gregory
ResearchOpen Access10 Jul 2024
Nature Communications

Volume: 15, P: 1-14
AI is a viable alternative to high throughput screening: a 318-target study

Izhar Wallach
Denzil Bernard
Abraham Heifets
ResearchOpen Access02 Apr 2024
Scientific Reports

Volume: 14, P: 1-16

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m3C32 tRNA modification controls serine codon-biased mRNA translation, cell cycle, and DNA-damage response

AI is a viable alternative to high throughput screening: a 318-target study

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m³C32 tRNA modification controls serine codon-biased mRNA translation, cell cycle, and DNA-damage response